[眶肌炎:超微结构和免疫组化研究]。

Archivos de neurobiologia Pub Date : 1990-11-01
M Cerdá-Nicolás, M Pérez Bacete, J Barberá Alacreu, A Peydró Olaya
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引用次数: 0

摘要

我们报告一例35岁男性眼眶肌炎患者的形态和超微结构研究,其定位不对称,临床表现为肿瘤。形态学检查显示慢性炎性病变,引起肌肉组织萎缩和坏死。在超微结构图像上,肌纤维明显萎缩,肌节萎缩,并伴有再生的迹象。炎症浸润呈多形性,免疫组织化学检测到T细胞和B细胞。通过形态学和免疫组化鉴定,巨噬细胞群α -1-胰酶和α -1-抗胰酶呈阳性。显示出一种重要的成纤维细胞活动。在讨论中,考虑了这种实体的可能发病机制。
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[Orbital myositis: an ultrastructural and immunohistochemical study].

We present a morphological and ultrastructural study from one case of orbitary myositis in a 35 years old male patient with asymmetrical localytation and clinical behaviour as a tumor. The morphological study shows a chronic inflammatory lesion which causes atrophy and necrosis of the muscular tissue. On the ultrastructural image it is remarkable the atrophy of the muscle fibers with loos of the sarcomers, joined with signs of regeneration. The inflammatory infiltrate is polimorfous, with T and B cells immunihistochemically detected. There is also a macrophagic population identified by the morphology and immunohistochemistry with positivity for alfa-1-chymiotrypsin and alfa-1-anti trypsin. An important fibroblastic activity is show. On the discussion a possible pathogenesis for this entity is considered.

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