(西综合症。[31例]。

Archivos de neurobiologia Pub Date : 1990-11-01
M I Cebrero García, R Simón de las Heras, F Mateos Beato, J Balseiro, J Torres Mohedas
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引用次数: 0

摘要

在这篇文章中,我们分析了31例诊断为韦斯特综合征的儿童的病因学、临床、脑电图、放射学、治疗和进化事实。诊断方法的进步,神经影像学的全面发展,使我们能够确定87%的病例的病因,原因有很大的可变性。ACTH和/或抗惊厥药物治疗有效;虽然对于患儿的预后,病因学和早期症状前的神经系统状况更为重要。因此,对所有隐发性病例和既往神经功能正常的继发性病例的临床进展均有利。其余70%的人仍然存在与危机相关或无关的智力迟缓。67.7%的病例脑电图仍然是病理的。5例发展为lenox - gastaut综合征,占全部病例的16%。
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[West syndrome. A series of 31 cases].

In this publish we analyze etiologic, clinic, electroencephalografic, radiologic, therapeutic and evolutionary facts of a serie of 31 children with diagnostic of West's syndrome. Advances in diagnostic methodes, overall of neuroimagen have allowed us to identify the etiology of 87% of cases, with a great variability of causes. The treatment with ACTH and/or anticonvulsive drugs was effective; although for children's prognostic, etiology and previous neurologic situation before initial symptomatology was more important. So, the clinical evolution was favorable for all criptogenetic cases and those secondary one with previous normal neurologic state. The rest, 70%, remained with mental delay, associated or no with crisis. Likewise the EEG persisted to be pathologic in 67.7% of cases. Five cases progressed towards Lennox-Gastaut's syndrome, that is to say, 16% of whole.

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