Interference, syndemia and neutrality of microbiota relationships as components of epidemic self-regulation

This article is dedicated to the outstanding scientist and figure of the national epidemiological doctrine, Academician of the Russian Academy of Medical Sciences Vitaly Belyakov. Through the prism of the events of recent years the advent of pandemics of socially significant infections a modern interpretation and confirmation of the relevance of the previously formulated theory of self-regulation of parasitic systems was given. The evolutionarily complex and diverse relationships between the microbiota and the animal world, its significant role in establishing a balance among many epidemic processes in the human population are considered and systematized. Particular attention is paid to the development of the human immunodeficiency virus and SARS-CoV-2 syndemic, as well as the latest observations of the interaction between the COVID-19 pathogen and the influenza virus. Data are presented that reflect the presence of interfering processes between the influenza virus and SARS-CoV-2, where for two years all isolated dangerous strains of SARS-CoV-2 prevented the arrival of seasonal epidemics of influenza and other acute respiratory viral infections. V. Belyakov in a certain historical format was ahead of events, describing the processes of self-regulation of the microcosm in the conditions of the macro- and microenvironment and its development, the patterns of which can be applied in the future.