自愿药物中毒:紧急化验室的流行病学、表现和限度。

A Rochette, E Le Niger, H Moulins, M Manchon
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引用次数: 0

摘要

本研究的目的是确定急性药物中毒期间毒理学筛查(巴比妥类药物、苯二氮卓类药物、三环抗抑郁药、水杨酸类药物、吩噻嗪类药物、甲丙酸酯和乙醇检测)的效率。1988年,898名患者被纳入这项研究。17%的病例筛查呈阴性;苯二氮卓类药物、酒精和抗抑郁药经常被发现。巴比妥类药物和水杨酸类药物的恢复效果很好,但苯二氮卓类药物的恢复效果并不理想,尤其是氟硝西泮、三唑安定、洛氟西泮、恶西泮和非三环抗抑郁药。这种故障可能与这些应急方法有关。
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[Voluntary drug poisoning: epidemiology, performance and limits of the emergency laboratory].

The aim of this study is to determine the efficiency ot toxicologic screening (detection of barbiturates, benzodiazepines, tricyclic antidepressants, salicylates, phenothiazines, meprobamate and ethanol assay), during acute drug poisoning. In 1988, 898 patients are enclose in this study. Screenings are negative in 17% of cases; benzodiazepines, alcohol and antidepressants are often found. The recovery is very good for barbiturates and salicylates but it's not perfect for benzodiazepines, particularly flunitrazepam triazolam, loflazepate, oxazepam, and non tricyclic antidepressants. This failure probably depends on these emergency methods.

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[Evaluation of 1st semester activity of the Algiers Poison Center]. [Acute amoxapine poisoning with rhabdomyolysis and acute renal insufficiency]. [A chemical necrosis]. [Rapid characterization of stupefacient and toxic substances by pressurized thin layer chromatography]. [Comparative urinary elimination of caffeine in sedentary and sportsmen after administration of Guronsan].
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