[两组口服镇静药物患儿行为比较]。

C Songvasin, A Pasavorakul
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引用次数: 0

摘要

本研究的目的是比较两组口服镇静药物:a)水合氯醛和异丙嗪和b)羟嗪和安定对儿童行为的影响。14名3至5岁的健康儿童参加了这项研究。所有儿童均表现出不良行为,需要至少两次使用口服镇静药物和氧化亚氮-氧气吸入镇静的恢复性预约。这些药物以双盲方式随机施用。在手术过程中评估睡眠、哭闹、运动和整体行为的程度。在睡眠方面,两组药物在孩子的行为上没有显著差异。在哭泣方面,注射和放置橡胶坝时,羟嗪和地西泮组儿童的哭泣明显少于水合氯醛和异丙嗪组(P < 0.05)。在运动方面,羟嗪和地西泮组儿童在注射、放置橡胶坝和间隔60分钟时的运动明显少于水合氯醛和异丙嗪组(P < 0.05)。在总体行为方面,羟嗪和地西泮组患儿表现优于水合氯醛和异丙嗪组患儿(P < 0.05)。
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[A comparison of the child's behavior between two groups of oral sedative drugs].

The purpose of this study was to compare the child's behavior between the two groups of oral sedative drugs: a) Chloral hydrate and Promethazine and b) Hydroxyzine and Diazepam. Fourteen healthy children, aged 3 to 5 years old, participated in this study. All children exhibited negative behavior and required at least two restorative appointments with the use of oral sedative drugs and nitrous oxide-oxygen inhalation sedation. The drugs were randomly administered in a double-blind manner. The degree of sleep, crying, movement and overall behavior were evaluated during the operative procedures. With respect to sleeping, there was no significant difference in the child's behavior between the two drug groups. With respect to crying, the children who had Hydroxyzine and Diazepam cried significantly less than when they had Chloral hydrate and Promethazine at the time of injection and rubber dam placement (P less than 0.05). With respect to movement, the children who had Hydroxyzine and Diazepam moved significantly less than when they had Chloral hydrate and Promethazine at the time of injection, rubber dam placement, and the 60 minute interval (P less than 0.05). For overall behavior, the children who had Hydroxyzine and Diazepam behaved better than when they had Chloral hydrate and Promethazine (P less than 0.05).

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