{"title":"[利什曼病:血清中存在因素的影响]。","authors":"D Savoia, A Cestaro, S Biglino","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>An important role in the interaction between protozoan parasite Leishmania and host is determined by serum factors. The activation of complement can have resistance-promoting effects (due to the lysis of parasite) or disease-promoting effect (due to the opsonization of Leishmania). Also lymphokines can determine resolution or progression of the infection. Particularly, gamma-interferon \"in vitro\" increases the killing of the parasite and \"in vivo\" cures cutaneous leishmaniasis.</p>","PeriodicalId":12722,"journal":{"name":"Giornale di batteriologia, virologia ed immunologia","volume":"83 1-12","pages":"118-24"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Leishmaniasis: effect of factors present in serum].\",\"authors\":\"D Savoia, A Cestaro, S Biglino\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>An important role in the interaction between protozoan parasite Leishmania and host is determined by serum factors. The activation of complement can have resistance-promoting effects (due to the lysis of parasite) or disease-promoting effect (due to the opsonization of Leishmania). Also lymphokines can determine resolution or progression of the infection. Particularly, gamma-interferon \\\"in vitro\\\" increases the killing of the parasite and \\\"in vivo\\\" cures cutaneous leishmaniasis.</p>\",\"PeriodicalId\":12722,\"journal\":{\"name\":\"Giornale di batteriologia, virologia ed immunologia\",\"volume\":\"83 1-12\",\"pages\":\"118-24\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Giornale di batteriologia, virologia ed immunologia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Giornale di batteriologia, virologia ed immunologia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[Leishmaniasis: effect of factors present in serum].
An important role in the interaction between protozoan parasite Leishmania and host is determined by serum factors. The activation of complement can have resistance-promoting effects (due to the lysis of parasite) or disease-promoting effect (due to the opsonization of Leishmania). Also lymphokines can determine resolution or progression of the infection. Particularly, gamma-interferon "in vitro" increases the killing of the parasite and "in vivo" cures cutaneous leishmaniasis.