[奥赛同步回旋加速器质子束的初步剂量学研究及其治疗应用]。

J C Rosenwald, A Bridier, R Sabattier, R Guillot, M Louis, P Schlienger, J L Habrand, L Desjardins, C Haye, E Bloch-Michel
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引用次数: 0

摘要

使用质子束治疗眼睛恶性肿瘤,允许对肿瘤体积进行高剂量照射,而对周围关键结构的照射可以忽略不计。实际上,波士顿和维利根的研究小组都有过这种技术的经验,他们报告的临床结果令人印象深刻。在法国,计划很快使用距离巴黎20公里的奥赛同步回旋加速器的200 MeV质子束。因此,在1988年进行了一项可行性研究,包括对奥赛质子束的特性进行剂量学分析。结论是,只需要简单的修改,使光束临床可用于质子治疗,更具体地说,用于治疗葡萄膜黑色素瘤。
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[Preliminary dosimetry study of the Orsay synchrocyclotron proton beam with a view to applying it therapeutically].

Using proton beams for treatment of malignant tumors of the eye allows high dose irradiation of the tumor volume with negligible irradiation of the surrounding critical structures. Actually, the clinical results reported from the Boston or Villigen groups which have experience of such a technique, are impressive. In France, it is planned to use soon 200 MeV proton beams from the Orsay synchrocyclotron 20 km from Paris. Therefore, a feasibility study has been conducted during year 1988, consisting of a dosimetric analysis of the characteristics of the Orsay proton beams. It was concluded that only simple modifications were necessary to make the beam clinically available for protontherapy and more specifically for treatment of uveal melanomas.

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