经皮射频脉冲传送心房除颤

G. Manoharan, J.A. Santos, N. Evans, J. Anderson, Bj Kidawi, J. Allen, A. Adgey
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引用次数: 0

摘要

心房颤动(AF)是最常见的持续性心律失常之一。其治疗需要使用同步电击或药物治疗。本文描述了一种新型的电除颤器,它采用两部分透皮射频变压器将一个开关键控7.2 MHz脉冲耦合到一个植入的被动接收器;这反过来又向心脏提供单极直流电击。讨论了影响变压器设计的因素,并给出了轴向和横向一次/二次线圈位移试验的结果。在动物实验中,当脉冲振幅为100 V,宽度为10 ms时,复律100%成功。这种植入物是无电池的,这使得它成为治疗心房颤动的一种有吸引力且廉价的选择。
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Atrial defibrillation using transcutaneous radio-frequency pulse delivery
Atrial fibrillation (AF) is one of the most common sustained cardiac arrhythmias found. Its treatment requires the use of a synchronised electrical shock or drug therapy. This paper describes a new form of electrical defibrillator that employs a two-part, transdermal RF transformer to couple an on-off keyed 7.2 MHz pulse to an implanted, passive receiver; this, in turn, delivers a unipolar DC shock to the heart. Factors influencing the transformer's design are discussed and results from axial and lateral primary/secondary coil displacement trials presented. In animal studies, cardioversion was 100% successful with pulses of 100 V amplitude and 10 ms width. The implant is battery-free, which makes it an attractive and inexpensive alternative for the treatment of AF.
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