[妇女宫颈鳞状细胞癌相关抗原的免疫细胞化学检测]。

Eksperimental'naia onkologiia Pub Date : 1990-01-01
E S Ievleva, N V Marshutina, A I Ageenko, B G Tsukerman
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引用次数: 0

摘要

用间接免疫荧光法对89例妇女宫颈标本进行了鳞状细胞宫颈癌相关抗原的检测。该抗原在77.8%的SCCC (Ib、II和III期)、64.3%的原位癌(原位癌和Ia期)、55.5%的非典型增生(II和III期)和17.2%的其他器官肿瘤样本中特异显示。在9名健康妇女的样本中未发现抗原。因此,检测与SCCC相关的抗原可能有助于制定辅助诊断和预后试验。
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[Immunocytochemical detection of antigen associated with squamous cell cancer of the cervix uteri in women].

Cervical preparations from 89 women were studied for antigen associated with squamous-cell cervical cancer (SCCC) by the indirect immunofluorescence method. The antigen was revealed specifically in 77.8% of samples of SCCC (stages Ib, II and III) in 64.3% of samples of cancer (in situ and stage Ia) in 55.5% of samples of displasia (stages II and III) and in 17.2% of samples from tumours of other organs. In samples of 9 healthy women the antigen was not revealed. Thus, the detection of antigen associated with SCCC may be useful in elaboration of adjuvant diagnostic and prognostic tests.

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