乳腺肿瘤浸润组织二维温度变化的数学研究

S. Shrestha, Gokul Kc, D. B. Gurung
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引用次数: 0

摘要

人体是由100万亿个细胞组成的。细胞不受控制和不正常的生长导致肿瘤。由于肿瘤的存在,机体的皮肤表面温度呈现出比正常异常的行为。乳腺肿瘤多发生于腺层小叶和乳管。本研究假定肿瘤位于腺层。本工作的研究重点是寻找不同肿瘤位置和不同肿瘤大小的女性乳腺组织中肿瘤包埋的温度分布。为此,采用有限元法求解二维Pennes生物热方程。结果表明,肿瘤离乳晕最近的乳房皮肤表面温度较高。肿瘤位于乳房中心线附近对称位置的乳腺组织温度变化相同。
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Mathematical Study of Two-Dimensional Temperature Variation in Tumor Embedded Breast Tissue
The human body is made by 100 trillion cells. The uncontrolled and abnormal growth of cells causes tumors. Due to the presence of tumor, the skin surface temperature of body provides abnormal behavior than normal. Most of the breast tumor develops in lobules and milk ducts of glandular layer. In this study, tumor is assumed in glandular layer. The study of this work is focused to find the temperature distribution in tumor embedded female breast tissue with different tumor location and different tumor size. For this, the finite element method is used to solve two-dimensional Pennes bio heat equation. The results show that the skin surface temperature of breast is higher with nearest tumor from areola. The temperature variation in breast tissue with tumors located at symmetrical position about the central line of the breast are identical.
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