皮肤-内脏利什曼病:HIV感染患者的一种新的机会性感染。

Q4 Medicine Medicina cutanea ibero-latino-americana Pub Date : 1990-01-01
R Botella Estrada, O Sanmartín Jiménez, M I Febrer Bosch, A Aliaga Boniche, M Salavert Lleti, P Roig Rico, A Nieto García, V Navarro Ibañez
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引用次数: 0

摘要

一名感染艾滋病毒的病人因发烧、腹泻和左腹股沟皮肤结节入院。组织病理学检查诊断为皮肤利什曼病。随后的检查发现内脏利什曼病。三个周期的治疗(锑、喷他脒和甲硝唑)需要清除病变。本文评述了免疫抑制与利什曼原虫感染的关系,并提出了利什曼原虫作为条件致病菌的作用。在这些患者中,感染的过程更具侵略性,对抗疟药的经典治疗反应更差。这些事实使得引入其他替代药物成为必要。
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[Cutaneo-visceral leishmaniasis: a new opportunistic infection in patients infected by HIV].

A HIV infected patient was admitted to hospital with fever diarrhoea and a cutaneous nodule on his left groin. Histopathological exam was diagnostic of cutaneous leishmaniasis. Subsequent exams disclosed Visceral Leishmaniasis. Three cycles of treatment (antimonials, pentamidine and metronidazole) were required for the clearance of lesions. The relation between immunosuppression and leishmania infection is commented and its role as an opportunistic pathogen is suggested. In these patients the infection takes a more aggressive course and has a worse response to the classic treatment with antimonials. These facts have made necessary the introduction of other alternative drugs.

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期刊介绍: La Revista Medicina Cutánea Ibero-Latino-Americana se adhiere a los “Requisitos de uniformidad para manuscritos presentados para publicación en revista biomédicas” elaborados por el Comité Internacional de Editores de Revista Médicas
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