Explicit role of platelet derived concentrates PRP and PRF in orthodontics - A detailed review

There has been significant growth and advancement since, the last few decades in the use of platelet and its derivatives in dentistry predominantly in oral surgery and periodontology. Very little is known about the same in orthodontics. There is emerging literature on the use of platelets and its derivatives in orthodontics. Platelets being the reservoir of cytokines and growth factors plays a crucial role in various regenerative processes. This review attempts to summarise the literature concerning to the application and role of platelet derived concentrates in orthodontics. The most commonly used platelet derived concentrates being the platelet-rich plasma (PRP) and Platelet-rich fibrin (PRF), their advancement and various roles and future opportunities of research have been described in this article.