对埃及老年人群不同样本中维生素D状况的评估

S. Shelbaya, S. Seddik, Abeer N. Ahmed, N. Roshdy, M. Abbas
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引用次数: 3

摘要

维生素D是参与钙稳态的重要激素之一。它对预防骨质疏松和骨折也是必不可少的。维生素D对维持许多生理功能都很重要,比如最佳平衡、肌肉力量和先天免疫。维生素D缺乏与几种癌症、自身免疫性疾病和心血管疾病的风险增加有关。由于饮食对维生素D状态的影响很小,大多数循环中的维生素D来自阳光照射,老年人受到的影响很大;它们有明显的限制,阻碍了它们暴露在阳光下,也阻碍了它们的进食和营养习惯。本研究的目的是评估埃及老年人、居家、养老院居民和流动老年人的维生素D状况。本研究共对90名老年男女进行研究,分为三组:第一组30名居家老年人,第二组30名敬老院老年人,第三组30名社区流动老年人。结果各组间维生素D水平差异有统计学意义,ⅲ组维生素D水平最高,为158 (18-240)nmol/l,ⅱ组维生素D水平最低,为16 (4-194)nmol/l。在阳光照射方面发现了统计学上的显著差异,第三组中60%的人有良好的阳光照射。饮食中维生素D的摄入量也有统计学上的差异,第三组64.30%的人摄入良好。第二组患者腰围最高(98.68±20.73 cm)。维生素D与II组血清钙呈显著正相关(ρ=0.199),与III组天冬氨酸转氨酶(AST)呈显著正相关(ρ=0.418)。结论:由于缺乏阳光照射、饮食问题和/或中枢性肥胖,埃及养老院的老年人有发生维生素D缺乏症的风险。
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Assessment of vitamin D status in different samples of an elderly Egyptian population
Introduction Vitamin D is one of the important hormones involved in Ca homeostasis. It is also essential for the prevention of osteoporosis and fractures. Vitamin D is important for maintaining many physiologic functions, such as optimal balance, muscle strength, and innate immunity. Vitamin D deficiency is associated with an increased risk for several types of cancer, as well as autoimmune and cardiovascular disorders. As the influence of diet on vitamin D status is minimal and most circulating vitamin D is derived from exposure to sunlight, elderly populations are greatly affected; they have marked limitations that hinder their exposure to sunlight as well as their feeding and nutritional habits. Objectives of the study The aim of this study was to assess vitamin D status in Egyptian geriatric, homebound, nursing home residents, and ambulatory elderly individuals. Patients and methods This study was carried out on 90 elderly male and female individuals divided into three groups: the first group included 30 homebound elderly individuals, the second group included 30 elderly individuals living in nursing homes, and the third group included 30 community-dwelling ambulatory elderly individuals. Results There were high statistically significant difference in the vitamin D levels between the groups studied, being the highest in group III, 158 (18–240) nmol/l, and the lowest in group II, 16 (4–194) nmol/l. Statistically significant differences were found in sun exposure, with good exposure in 60% of the individuals in group III. There were also statistically significant differences in the intake of vitamin D in diet, with good intake in 64.30% of the individuals in group III. Also, we found the highest waist circumference in group II (98.68±20.73 cm). Vitamin D showed a significant positive correlation with serum calcium in group II (ρ=0.199) and a positive correlation with aspartate transaminase (AST) in group III (ρ=0.418). Conclusion Elderly Egyptian individuals in nursing houses are at risk of developing vitamin D deficiency because of lack of exposure to sunlight, dietary problems, and or central obesity.
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