麻疹病毒

M. Oldstone
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引用次数: 0

摘要

本章探讨人类历史进程中麻疹病毒的起源和传染性。麻疹最初是如何感染人类的尚不清楚。由于麻疹病毒感染曾经几乎不可能与天花病毒感染区分开来,因此很难获得确切的证据。因此,两者被合并为一个实体。早在10世纪,阿拉伯医生阿布·贝克尔(Abu Becr)就首次试图区分这两者。然而,直到17世纪,英国医生托马斯·西德纳姆才真正记录了麻疹感染的临床实体。一旦人们了解到感染麻疹病毒可以终身预防麻疹,并且人类是天然宿主,人们的兴趣就转向了开发一种预防性疫苗。然后,本章考虑了麻疹病毒疫苗可能有害的传闻证据。这种错误信息往往是出于个人原因而传播的,但却极大地影响了公众健康和个人生活。
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Measles Virus
This chapter explores the origin and infectivity of the measles virus in the course of human history. How measles first came to infect humans is not clear. Definitive proof is hard to come by since measles virus infection was once nearly impossible to distinguish from smallpox virus infection. Consequently, both had been lumped together as a single entity. As early as the tenth century, the Arab physician Abu Becr first attempted to distinguish between the two. However, it was not until the seventeenth century that English physician Thomas Sydenham actually documented the clinical entity of measles infection. Once it was understood that infection with measles virus confers lifelong protection from the disease and that humans are the natural host, interest turned toward developing a preventive vaccine. The chapter then considers the purported evidence that measles virus vaccines may be harmful. Such misinformation is often propagated for personal reasons yet greatly affects public health and individual lives.
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