[动物模型中的龋齿]。

J P Loyola, P Leyva
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引用次数: 0

摘要

用g型变形链球菌接种sd - dawley大鼠,研究了日粮中不同浓度(20%、40%和56%)蔗糖对该菌株在大鼠口腔内的建立的影响。变形链球菌在所有实验组中都存在,我们发现蔗糖浓度与龋齿严重程度之间几乎呈线性相关。另一个影响变异链球菌进入大鼠口腔的重要因素是接种量的大小。在这项工作中,浓度为4 × 10(10)显示在该动物模型的牙齿上建立一致。
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[Dental caries in an animal model].

Sprague-Dawley rats were inoculated with Streptococcus mutans (serotype g) and the effect of different concentrations (20, 40 and 56%) of sucrose in the diet on the establishment of this strain into the oral cavity of rats was studied. The Streptococcus mutans was well established in all the experimental groups and we found an almost linear correlation between the sucrose concentration and the severity of dental caries. Another factor that played an important role on the establishment of Streptococcus mutans into the mouth of rats was the inoculum size used. In this work a concentration of 4 x 10(10) showed a consistent establishment onto the teeth of this animal model.

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