J Malejczyk, S Majewski, W Gliński, L Rudnicka, M Malejczyk
{"title":"自然杀伤细胞对关节关节炎合并银屑病和系统性硬皮病患者软骨细胞的毒性研究。","authors":"J Malejczyk, S Majewski, W Gliński, L Rudnicka, M Malejczyk","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The natural killer (NK) activity against fetal chondrocytes was studied in patients with psoriasis and systemic sclerosis. It was shown that the cell responsible for the cytotoxic effect is a lymphocyte CD16+, CD2-. In patients with arthritic psoriasis NK activity against chondrocytes was significantly higher than in other psoriasis patients or in healthy controls. Preliminary studies show that the NK activity against chondrocytes is decreased in patients with systemic sclerosis.</p>","PeriodicalId":20732,"journal":{"name":"Przeglad dermatologiczny","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"1990-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Studies of natural killer cell cytotoxicity against human chondrocytes in patients with articular arthritic changes complicated by psoriasis and systemic scleroderma].\",\"authors\":\"J Malejczyk, S Majewski, W Gliński, L Rudnicka, M Malejczyk\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The natural killer (NK) activity against fetal chondrocytes was studied in patients with psoriasis and systemic sclerosis. It was shown that the cell responsible for the cytotoxic effect is a lymphocyte CD16+, CD2-. In patients with arthritic psoriasis NK activity against chondrocytes was significantly higher than in other psoriasis patients or in healthy controls. Preliminary studies show that the NK activity against chondrocytes is decreased in patients with systemic sclerosis.</p>\",\"PeriodicalId\":20732,\"journal\":{\"name\":\"Przeglad dermatologiczny\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.5000,\"publicationDate\":\"1990-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Przeglad dermatologiczny\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"DERMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Przeglad dermatologiczny","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}
[Studies of natural killer cell cytotoxicity against human chondrocytes in patients with articular arthritic changes complicated by psoriasis and systemic scleroderma].
The natural killer (NK) activity against fetal chondrocytes was studied in patients with psoriasis and systemic sclerosis. It was shown that the cell responsible for the cytotoxic effect is a lymphocyte CD16+, CD2-. In patients with arthritic psoriasis NK activity against chondrocytes was significantly higher than in other psoriasis patients or in healthy controls. Preliminary studies show that the NK activity against chondrocytes is decreased in patients with systemic sclerosis.
期刊介绍：
Przegląd Dermatologiczny (ang. Dermatological Review) is a bimonthly magazine of the Polish Dermatological Association. It publishes original (clinical and experimental) papers, review papers, care reports, reports from congresses, reviews of books, announcements, letters to the editor and special papers (requested by the editors), concerning selected dermatological and interdisciplinary issues. Papers sent to the editor are reviewed.
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