辛伐他汀与福美甲索治疗去牙乳牙的临床及影像学评价。

Abdel Aaty Abdel Aaty, Ibrahim Barkat, Al-baraa Abbas
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摘要

目的:本研究旨在评价辛伐他汀作为第一磨牙切髓药物的效果,确定其临床和影像学成功率,并与福摩甲酚(FC)进行比较。对象与方法:选取年龄在3 ~ 7岁的儿童,共80颗需要行切髓术的龋齿。根据用药情况将受累牙分为两组;A组;去髓牙接受辛伐他汀治疗;B组;去牙髓的牙齿接受福摩甲酚治疗。分别在1周、3个月和6个月后按照特定标准进行临床和影像学评估。结果:去髓牙接受福摩甲酚治疗的成功率略高,辛伐他汀与福摩甲酚治疗的临床和影像学成功率相当,差异无统计学意义。结论:辛伐他汀可作为福摩甲酚的有效替代药物治疗去牙乳牙。
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Clinical and Radiographic Evaluation of Simvastatin Versus Formecresol in Treatment Pulpotomized Primary Teeth.
Objectives: This study was directed to evaluate the effect of simvastatin as pulpotomy medicament in the primary molar teeth, to determine its clinical and radiographic success rate and to compare it with formocresol (FC). Subjects and Methods: Children aged between 3-7 years which had a total of 80 decayed primary molar teeth indicated for pulpotomy treatment were included in this study. The involved teeth were grouped into two groups according to the received medicament; Group A; Pulpotomized teeth received simvastatin; Group B; Pulpotomized teeth received formocresol. The clinical and radiographic evaluation were made after 1-week, 3-months, and 6-months follow specific criteria. Results: Pulpotomized teeth which received formocresol showed slightly higher success rate, but both of simvastatin and formocresol treated teeth showed comparable clinical and radiographic clinical success rates with no statistically significant difference. Conclusion: Simvastatin can be used as effective alternative medicament for formocresol in the treatment of pulpotomized primary molar teeth.
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