[可的芬对人肿瘤株移植胸腺小鼠和大鼠的影响]。

Eksperimental'naia onkologiia Pub Date : 1990-01-01

I K Bukharova, E S Revazova, L V Moroz

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引用次数: 0

摘要

在苏联医学科学院全联盟癌症研究中心合成的可的芬的抗肿瘤活性在移植到裸鼠和大鼠体内的人类肿瘤株上进行了研究。对肾癌、子宫癌、绒毛膜上皮瘤、纤维肉瘤等均有表达活性。三种大肠腺癌中有两种对皮质酚表现出表达敏感性，而黑色素瘤和犹太肉瘤株对该制剂表现出弱敏感性。

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[Effects of cortiphen on human tumor strains transplanted into athymic mice and rats].

The antitumour activity of cortiphen synthesized at the All-Union Cancer Research Centre of the USSR Academy of Medical Sciences was studied on human tumour strains transplanted into nude mice and rats. Cortiphen was found to possess an expressed activity to kidney cancer, cancer of corpus uteri, chorionepithelioma, fibrosarcoma. Two strains of colon adenocarcinoma out of three have displayed an expressed sensitivity to cortiphen, while melanoma and Jewing sarcoma strains proved to be weakly sensitive to the preparation.

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Eksperimental'naia onkologiia

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