泰伦加纳邦一家三级医院精神科门诊患者抑郁和焦虑症的处方模式

Jagathi Nagari, Kavitha Mudavath, Sangeeta Jairaj, Neilofor Hussain
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摘要

抑郁和焦虑是在精神科门诊就诊的病人中最常见的精神疾病。大多数抗抑郁药和抗焦虑药的相对安全性增加了它们的常规使用。然而,关于这些药物的处方模式的数据有限,特别是来自特伦加纳邦的数据。本研究的目的是评估特伦加纳邦一家三级护理教学医院精神科门诊患者的抑郁和焦虑障碍处方模式。在纳尔贡达政府总医院(GGH)精神病学门诊部进行了为期6个月的前瞻性观察研究(2021年3月至2021年8月)。根据国际疾病分类第10版(ICD-10),共选择了45名焦虑和抑郁患者。采用半结构化形式收集数据并进行分析。处方共103种药物,平均每张处方药物数为2.29种。患者以15 ~ 35岁(60%)、女性(62.22%)、已婚(60%)、城市背景(82.2%)居多。在研究人群中,55.55%患有焦虑症,其中31.11%患有广泛性焦虑症。抑郁症患者以重度抑郁发作为主(占44.45%),占26.67%,其次为中度抑郁发作(占17.78%)。病程小于6个月的患者占多数(75.56%)。选择性血清素再摄取抑制剂(SSRIs)是最常见的药物处方组。41张处方中含有SSRIs类药物,占91.11%,以舍曲林最多,其次为艾司西酞普兰,苯二氮卓类药物(氯硝西泮)占93.33%。35.55%的处方为固定剂量组合,以艾司西酞普兰10mg +氯硝西泮0.5mg最为常见。
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Prescription pattern of depressive and anxiety disorders in patients attending Psychiatry outpatient department of a tertiary hospital in Telangana
Depression and anxiety are the most common mental illnesses encountered in patients visiting psychiatry outpatient clinics. The relative safety of majority of antidepressants and anxiolytics has increased their routine use. However, limited data is available on the prescribing patterns of these drugs, especially from the state of Telangana. The aim of this study was to assess the prescription pattern in depression and anxiety disorders in patients attending Psychiatry outpatient department of a tertiary care teaching hospital in Telangana. A prospective observational study was conducted in Psychiatry outpatient department in Government General Hospital (GGH), Nalgonda over a period of 6 months (March 2021 to August 2021). A total of 45 patients suffering from anxiety and depression, based on International Classification of Diseases-10th edition (ICD-10), were selected. Data was collected using a semi-structured proforma and analyzed. A total of 103 drugs were prescribed and the average number of drugs per prescription was 2.29. It was found that majority of patients were in 15-35 years age group (60%), female (62.22%), married (60%) and from urban background (82.2%). In the study population, 55.55% were suffering from anxiety disorders, out of which 31.11% had Generalized anxiety disorder. Among the depressive disorders (44.45%) majority had Severe depressive episode (26.67%) followed by Moderate depressive episode (17.78%). The duration of illness was less than 6 months in majority of patients (75.56%). Selective serotonin reuptake inhibitors (SSRIs) were the most common group of drugs prescribed. 41 prescriptions (91.11%) contained SSRIs, and Sertraline was the most common drug followed by Escitalopram. 93.33% of the prescriptions also included Benzodiazepines (Clonazepam). 35.55% of the prescriptions had fixed dose combinations, commonest being Escitalopram 10mg + Clonazepam 0.5mg.
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