{"title":"本地临床试验:改善全球癌症治疗的迫切需要","authors":"Apar Kishor Ganti","doi":"10.1055/s-0043-1768568","DOIUrl":null,"url":null,"abstract":"Advances in the care of cancer patients are almost always due to clinical trials that demonstrate improved patient outcomes in terms of better survival or improved quality of life. Pharmaceutical companies invest a large amount of time, effort, and money in developing novel agents, but only a few of these end up actually changing patient care. Agents such as imatinib, osimertinib, trastuzumab, rituximab, and pembrolizumab, among others, are prime examples of this approach. A recent analysis found that the median cost of development of an anticancer drug was $648.0 million.[1]","PeriodicalId":13513,"journal":{"name":"Indian Journal of Medical and Paediatric Oncology","volume":"19 1","pages":"0"},"PeriodicalIF":0.3000,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Local Clinical Trials: The Need of the Hour to Improve Global Cancer Care\",\"authors\":\"Apar Kishor Ganti\",\"doi\":\"10.1055/s-0043-1768568\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Advances in the care of cancer patients are almost always due to clinical trials that demonstrate improved patient outcomes in terms of better survival or improved quality of life. Pharmaceutical companies invest a large amount of time, effort, and money in developing novel agents, but only a few of these end up actually changing patient care. Agents such as imatinib, osimertinib, trastuzumab, rituximab, and pembrolizumab, among others, are prime examples of this approach. A recent analysis found that the median cost of development of an anticancer drug was $648.0 million.[1]\",\"PeriodicalId\":13513,\"journal\":{\"name\":\"Indian Journal of Medical and Paediatric Oncology\",\"volume\":\"19 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2023-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Medical and Paediatric Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1055/s-0043-1768568\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Medical and Paediatric Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/s-0043-1768568","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ONCOLOGY","Score":null,"Total":0}
Local Clinical Trials: The Need of the Hour to Improve Global Cancer Care
Advances in the care of cancer patients are almost always due to clinical trials that demonstrate improved patient outcomes in terms of better survival or improved quality of life. Pharmaceutical companies invest a large amount of time, effort, and money in developing novel agents, but only a few of these end up actually changing patient care. Agents such as imatinib, osimertinib, trastuzumab, rituximab, and pembrolizumab, among others, are prime examples of this approach. A recent analysis found that the median cost of development of an anticancer drug was $648.0 million.[1]
期刊介绍:
The journal will cover technical and clinical studies related to medical and pediatric oncology in human well being including ethical and social issues. Articles with clinical interest and implications will be given preference.