Il cortisone non è più efficace della soluzione fisiologica nei disturbi respiratori del sonno: i risultati di un RCT

Cortisone is no more effective than saline in sleep-disordered breathing: results of an RCT Sleep disordered breathing (SDB) affects about 12% of children. An Australian multicentre, randomised, double-blind, placebo-controlled clinical trial conducted in third-level centres, intends to verify the efficacy of intranasal mometasone in improving the symptoms and quality of life of children with SDB compared with an intranasal saline solution. 276 subjects aged between 3 and 12 years with SDB were recruited. The results did not show any difference between the two treatments. In fact, both groups recorded an equal percentage of improvement in symptoms, which could be due in both groups to the treatment or to the natural evolution of the picture. This leads the authors to state that a proportion of children with SDB could be managed in the primary care setting.