某些药用植物的薄层色谱分析及其抗氧化和抗糖尿病活性

Richa Dodia, Susmita Sahoo
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摘要

糖尿病是一种发病率在全球各地迅速上升的疾病。据联合国机构世界卫生组织(WHO)称,到2030年,多基因疾病将成为第七大死亡原因。在印度医学体系和世界上不同的古代体系中,一些健康的植物,如瓜蒌、葫芦巴和穆拉亚被用于治疗糖尿病疾病。这三片植物叶子是在古吉拉特邦的Vadodara和Anand收集的。这三种植物叶片的薄层色谱分析证实了在这两个城市中存在各种常见类型的植物化学物质,如芦丁、没食子酸、单宁酸和槲皮素。薄层色谱分析表明,保留系数在0.01 ~ 0.97之间。另外,毛茛、黄叶茅和柯尼姬植物叶片均具有抗氧化和抗糖尿病活性,但阿南德市毛茛的抗氧化和抗糖尿病活性最好。这项研究将有助于在未来确定这种植物,以供工业和制药公司进一步研究。
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Thin Layer Chromatographic Profiling, Antioxidant and Antidiabetic Activity of Selected Medicinal Plants
Diabetes mellitus is a disorder whose frequency is speedily increasing everywhere on the planet. According to the World HealthOrganization (WHO), a United Nations Agency, polygenic diseases are going to be the seventh leading reason for death in 2030. Several healthful plants like Citrullus lanatus, Trigonella foenum-graecum, and Murraya koenigii are used for the treatment of diabetes disorders in the Indian medicine system and different ancient systems of the world. These three plant leaves were collected from Vadodara and Anand, Gujarat. Thin layer chromatography profiling of all three plant leaves confirmed the presence of various common classes of phytochemicals such as rutin, gallic acid, tannic acid, and quercetin in both cities. Thin layer chromatographic analysis of a particular leaf revealed various retention factor values in the range of 0.01 to 0.97. Also, C. lanatus, T. foenum-graecum, and M. koenigii plant leaves confirmed the antioxidant and antidiabetic activity but C. lanatus from Anand city was found to be the best plant. The study will help in the future to identify this plant for further research in industries and pharmaceutical companies.
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