用于测定吸入液体药物预期剂量的雾化过程的质量和体积平衡

IF 0.5 4区工程技术 Q4 ENGINEERING, CHEMICAL Chemical and Process Engineering-Inzynieria Chemiczna I Procesowa Pub Date : 2023-11-06 DOI:10.24425/cpe.2021.138929

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Mass and volume balances of nebulization processes for the determination of the expected dose of liquid medicines delivered by inhalation

The works presents the application of mass/volume balances of liquid drug converted into the aerosol during atomization in medical nebulizers. The amount of liquid that can be delivered to the respiratory system during inhalation is reduced compared to the nominal dose not only because of drug losses both in the device (the residual volume, RV ) and outside the nebulizer (in the mouthpiece, mask, or tubings), but also to the limitations of the patient (periodic ﬂow with limited capacity). The paper should help to understand the complexity of aerosol therapy widely used in asthma, COPD and other pulmonary diseases

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来源期刊

Chemical and Process Engineering-Inzynieria Chemiczna I Procesowa 工程技术-工程：化工

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The content, aim and scope of the proposals should comply with the main subject of the journal, i.e. they should deal with mathematical modelling and/or experimental investigations on momentum, heat and mass transfer, unit processes and operations, integrated processes, biochemical engineering, statics and kinetics of chemical reactions. The experiments and modelling may cover different scales and processes ranging from the molecular phenomena up to production systems. The journal language is grammatically correct British English. Chemical and Process Engineering publishes: i) full text research articles, ii) invited reviews, iii) letters to the editor and iv) short communications, aiming at important new results and/or applications. Each of the publication form is peer-reviewed by at least two independent referees.