慢性肾病患者感染 SARS-CoV-2(严重急性呼吸道冠状病毒 2)的预防和治疗策略:文献综述。

IF 2 4区 医学 Q2 UROLOGY & NEPHROLOGY Nefrologia Pub Date : 2024-03-01 DOI:10.1016/j.nefro.2023.10.002
María Marques Vida , Elena Muñez Rubio , Borja Quiroga , Rocío Montejano , Enrique Morales , Francisco Javier Candel
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引用次数: 0

摘要

事实证明,COVID-19 对慢性肾脏病(CKD)患者的侵袭性特别强。慢性肾病患者的免疫反应率较低,更容易发展成严重的疾病,这是造成这种现象的原因之一,而且这种现象在疫苗接种后的大流行时代依然存在。矛盾的是,在针对 SARS-CoV-2 开发的主要治疗工具的大多数临床试验中,慢性肾功能衰竭都被排除在外。本综述的目的是收集 COVID-19 在疾病不同阶段的所有治疗适应症,以适应不同阶段的 CKD,包括肾脏替代疗法。
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Estrategias de prevención y tratamiento de la infección por SARS-CoV-2 (Severe Acute Respiratory Coronavirus 2) en pacientes con enfermedad renal crónica: revisión de la literatura

COVID-19 has proven to be particularly aggressive in patients with chronic kidney disease (CKD). The lower immune response rate and the greater susceptibility to progress to severe forms of the disease have contributed to this phenomenon, which has persisted in the post-vaccination era of the pandemic. Paradoxically, CKD has been excluded from most clinical trials of the main therapeutic tools developed against SARS-CoV-2. However, experience in the use of these drugs has been accumulating in different stages of CKD, supporting their use with guarantees of efficacy and safety.

The objective of this review is to gather all treatment indications for COVID-19 in the different phases of the disease, tailored to CKD in its various stages, including renal replacement therapy.

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来源期刊
Nefrologia
Nefrologia 医学-泌尿学与肾脏学
CiteScore
3.40
自引率
7.70%
发文量
148
审稿时长
47 days
期刊介绍: Nefrología is the official publication of the Spanish Society of Nephrology. The Journal publishes articles on basic or clinical research relating to nephrology, arterial hypertension, dialysis and kidney transplants. It is governed by the peer review system and all original papers are subject to internal assessment and external reviews. The journal accepts submissions of articles in English and in Spanish languages.
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