灵长类动物卵泡成熟的旁分泌调节

Sharon A. Tonetta, Gere S. dizerega
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引用次数: 16

摘要

综上所述,本文综述的研究表明,虽然促性腺激素是卵泡生长所必需的,但它们本身不足以解释卵泡发生的动力学。事实上,促性腺激素在卵泡成熟中的作用必须是允许的:即LH和FSH启动由旁分泌和自分泌因素直接介导的同步级联卵泡事件。
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7 Paracrine regulation of follicular maturation in primates

Taken together, the studies reviewed here suggest that although gonadotropins are necessary for follicular growth, they are insufficient by themselves to explain the dynamics of folliculogenesis. Indeed, the role of gonadotropins in follicular maturation must necessarily be permissive: that is LH and FSH initiate a synchronized cascade of follicular events directly mediated by paracrine and autocrine factors.

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