具有自身免疫特征的间质性肺炎：旨在定义、完善和治疗

Q3 Health Professions Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI:10.1016/j.rcreu.2023.07.006

Elena K. Joerns , Jeffrey A. Sparks

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引用次数: 0

摘要

出于研究目的，具有自身免疫特征的间质性肺炎（IPAF）被定义为与自身免疫特征相关的间质性肺病（ILD），但未确诊为风湿病（RD）。自2015年发布IPAF标准以来，已有多项关于IPAF的研究。然而，关于 IPAF 的发病机制、预后和治疗仍有许多未知之处。这篇叙述性综述详细介绍了 IPAF 的历史和分类，列出了将患者分类为 IPAF 所面临的挑战，并探讨了 IPAF 的患病率、流行病学和表现形式。我们还研究了预后和决定 IPAF 临床过程的重要特征，概述了发病机制，并综述了治疗策略。

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Interstitial pneumonia with autoimmune features: Aiming to define, refine, and treat

Interstitial pneumonia with autoimmune features (IPAF) was defined for research purposes as interstitial lung disease (ILD) associated with features of autoimmunity without diagnosed rheumatic disease (RD). Since publication of the IPAF criteria in 2015, there have been multiple studies of IPAF. However, much remains unknown regarding pathogenesis, prognosis, and treatment in IPAF. This narrative review details the history and classification of IPAF, lists challenges associated with classifying patients as IPAF, and explores the prevalence, epidemiology, and presentation of IPAF. We also examine prognosis and important features determining IPAF clinical course, outline pathogenesis, and review treatment strategies.

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来源期刊

Revista Colombiana de Reumatologia Medicine-Rheumatology

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The Colombian Journal of Rheumatology (Revista Colombiana de Reumatología) is the official organ of the Colombian Association of Rheumatology (Asociación Colombiana de Reumatología) and the Central American, Caribbean and Andean Association of Rheumatology (Asociación Centroamericana Caribe Andina de Reumatología) - ACCA. It was created in December 1993 with the purpose of disseminating scientific information derived from primary and secondary research and presenting cases coming from the practice of Rheumatology in Latin America. Since its foundation, the Journal has been characterized by its plurality with subjects of all rheumatic and osteomuscular pathologies, in the form of original articles, historical articles, economic evaluations, and articles of reflection and education in Medicine. It covers an extensive area of topics ranging from the broad spectrum of the clinical aspects of rheumatology and related areas in autoimmunity (both in pediatric and adult pathologies), to aspects of basic sciences. It is an academic tool for the different members of the academic and scientific community at their different levels of training, from undergraduate to post-doctoral degrees, managing to integrate all actors inter and trans disciplinarily. It is intended for rheumatologists, general internists, specialists in related areas, and general practitioners in the country and abroad. It has become an important space in the work of all rheumatologists from Central and South America.