{"title":"1%特比萘芬乳膏与1%克霉唑乳膏治疗足癣的比较研究","authors":"Araz Hasan Mohammed, Gulikhan Ahmed Omer","doi":"10.26505/djm.24016880824","DOIUrl":null,"url":null,"abstract":"Background:Tinea pedis (athletic foot) is the most common dermatophytic fungal infection of the body. It may last for a short or long time and may recur after treatment. Objective: To assessed and compared the effectiveness and safety of 1% terbinafine cream and 1% clotrimazole cream for the treatment of tinea pedis. Patients and Methods: Randomized control trial was done in the outpatient clinic of dermatology department in Rizgary Teaching Hospital in Erbil. From March, 2019 to January, 2020. Sixty patients with tinea pedis diag-nosed clinically were included in this study. Thirty patients applied 1% terbinafine cream topically twice daily for one week and thirty patients applied 1% clotrimazole cream topically twice daily for four weeks. Scraping for fungi was performed before and after therapy. Efficacy was assessed by clini-cal cure and mycological cure. Clinical and mycological cure measured at weeks one, four and six. Results: Mycological cure rates were 86.7% for terbinafine and 80% for clotrimazole at 4 weeks, 86.7% for terbinafine and 90% for clotrimazole at 6 weeks. At 4 weeks, terbinafine had an 83.3 percent clinical treatment rate and clotrimazole had a 76.67 percent clinical treatment rate; at 6 weeks, terbinafine had an 83.3 percent clinical treatment rate and clotrimazole had an 83.3 percent clinical treatment rate. Conclusion: The study showed that one week terbinafine two times a day is as effective as four weeks clotrimazole two times a day as well as in terms of mycological treatments and efficient therapies.","PeriodicalId":11202,"journal":{"name":"Diyala Journal of Medicine","volume":"125 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparative Study of Topical 1% Terbinafine Cream Versus 1% Clotrimazole Cream in The Treatment of Tineapedis\",\"authors\":\"Araz Hasan Mohammed, Gulikhan Ahmed Omer\",\"doi\":\"10.26505/djm.24016880824\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background:Tinea pedis (athletic foot) is the most common dermatophytic fungal infection of the body. It may last for a short or long time and may recur after treatment. Objective: To assessed and compared the effectiveness and safety of 1% terbinafine cream and 1% clotrimazole cream for the treatment of tinea pedis. Patients and Methods: Randomized control trial was done in the outpatient clinic of dermatology department in Rizgary Teaching Hospital in Erbil. From March, 2019 to January, 2020. Sixty patients with tinea pedis diag-nosed clinically were included in this study. Thirty patients applied 1% terbinafine cream topically twice daily for one week and thirty patients applied 1% clotrimazole cream topically twice daily for four weeks. Scraping for fungi was performed before and after therapy. Efficacy was assessed by clini-cal cure and mycological cure. Clinical and mycological cure measured at weeks one, four and six. Results: Mycological cure rates were 86.7% for terbinafine and 80% for clotrimazole at 4 weeks, 86.7% for terbinafine and 90% for clotrimazole at 6 weeks. At 4 weeks, terbinafine had an 83.3 percent clinical treatment rate and clotrimazole had a 76.67 percent clinical treatment rate; at 6 weeks, terbinafine had an 83.3 percent clinical treatment rate and clotrimazole had an 83.3 percent clinical treatment rate. Conclusion: The study showed that one week terbinafine two times a day is as effective as four weeks clotrimazole two times a day as well as in terms of mycological treatments and efficient therapies.\",\"PeriodicalId\":11202,\"journal\":{\"name\":\"Diyala Journal of Medicine\",\"volume\":\"125 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diyala Journal of Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26505/djm.24016880824\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diyala Journal of Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26505/djm.24016880824","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Comparative Study of Topical 1% Terbinafine Cream Versus 1% Clotrimazole Cream in The Treatment of Tineapedis
Background:Tinea pedis (athletic foot) is the most common dermatophytic fungal infection of the body. It may last for a short or long time and may recur after treatment. Objective: To assessed and compared the effectiveness and safety of 1% terbinafine cream and 1% clotrimazole cream for the treatment of tinea pedis. Patients and Methods: Randomized control trial was done in the outpatient clinic of dermatology department in Rizgary Teaching Hospital in Erbil. From March, 2019 to January, 2020. Sixty patients with tinea pedis diag-nosed clinically were included in this study. Thirty patients applied 1% terbinafine cream topically twice daily for one week and thirty patients applied 1% clotrimazole cream topically twice daily for four weeks. Scraping for fungi was performed before and after therapy. Efficacy was assessed by clini-cal cure and mycological cure. Clinical and mycological cure measured at weeks one, four and six. Results: Mycological cure rates were 86.7% for terbinafine and 80% for clotrimazole at 4 weeks, 86.7% for terbinafine and 90% for clotrimazole at 6 weeks. At 4 weeks, terbinafine had an 83.3 percent clinical treatment rate and clotrimazole had a 76.67 percent clinical treatment rate; at 6 weeks, terbinafine had an 83.3 percent clinical treatment rate and clotrimazole had an 83.3 percent clinical treatment rate. Conclusion: The study showed that one week terbinafine two times a day is as effective as four weeks clotrimazole two times a day as well as in terms of mycological treatments and efficient therapies.