【癌痛的治疗——综合治疗理念】。

Archiv fur Geschwulstforschung Pub Date : 1989-01-01
G Tontschev
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引用次数: 0

摘要

提出了癌症疼痛治疗的综合概念。医学镇痛药物治疗代表了这一概念的要点,按照世界卫生组织推荐的三级镇痛阶梯加以应用。这种疗法可以实现个体适应反应。非麻醉性镇痛药、弱、强阿片类药物及辅助药物的使用可增加镇痛强度。除了说明其使用原理和几种药物的详细剂量外,还提到了可能的副作用和相互作用,并引用了一些临床应用的例子。局部椎管内应用吗啡可进一步增加镇痛强度。为此,使用硬膜外和鞘内长期导管。在这些病例中,也提到了剂量、副作用和并发症,并讨论了使用可植入系统(疼痛端口)和外部便携式或可植入泵进行持续镇痛的可能性和优点。此外,还提到了神经溶解阻滞、神经外科治疗和放射治疗在这一概念中的作用。
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[Therapy of cancer pain--a comprehensive therapy concept].

A comprehensive conception for cancer pain treatment is presented. The medical analgesic drug therapy representing the main point of this conception is applied as a three steps analgesic ladder as recommend by the WHO. This kind of therapy enables an individual adaptation resp. increase of the analgesic intensity by the use of non narcotic analgetics, weak and strong opioids as well as adjuvant drugs. Besides the explanation of the principles of its application and some detailed instructions for the dosage of several drugs, possible side effects and interactions are mentioned as well as some examples for its clinical application are quoted. A further increase of the analgesic intensity is reached by the local intraspinal application of morphine. For this purpose epidural and intrathecal long-term catheters are used. Also in these cases dosage, side effects and complications are mentioned and the possibilities and advantages of the continuous analgesia with implantable systems (pain ports) and external portable or implantable pumps are discussed. Furthermore the role of the neurolytic blocks, neurosurgical treatment and radiation therapy within this conception is mentioned.

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