{"title":"Theranekron®和米索前列醇对大鼠肝部分切除后再生作用的研究","authors":"İsmet Yılmaz, Burhan Hakan Kanat, Azibe Yildiz","doi":"10.47363/jtmtr/2023(2)109","DOIUrl":null,"url":null,"abstract":"In the present study we were aimed to investigate/compare regenerative effects of Theranekron® (TC) and Misoprostol (MS) after Partial Hepatectomy (PH) in rats. This study was conducted in 38 rats, they were divided in to 5 groups and 7 days study periot. When considering biochemical and histopathological results; we were seen that after PH 7 days duration was not sufficient and also at least 10 days periot may be necessary. Although some literatures were reported about positive effects of TC and MS on epithelial growing, we have not seen that they have not any positive effect on liver regeneration. In the future -at different doses and durations- these may be found effective.","PeriodicalId":489498,"journal":{"name":"Journal of Translational Medicine & Transplantation Research","volume":"54 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Investigation of Regenerative Effects of Theranekron® and Misoprostol after Partial Hepatectomy in Rats\",\"authors\":\"İsmet Yılmaz, Burhan Hakan Kanat, Azibe Yildiz\",\"doi\":\"10.47363/jtmtr/2023(2)109\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the present study we were aimed to investigate/compare regenerative effects of Theranekron® (TC) and Misoprostol (MS) after Partial Hepatectomy (PH) in rats. This study was conducted in 38 rats, they were divided in to 5 groups and 7 days study periot. When considering biochemical and histopathological results; we were seen that after PH 7 days duration was not sufficient and also at least 10 days periot may be necessary. Although some literatures were reported about positive effects of TC and MS on epithelial growing, we have not seen that they have not any positive effect on liver regeneration. In the future -at different doses and durations- these may be found effective.\",\"PeriodicalId\":489498,\"journal\":{\"name\":\"Journal of Translational Medicine & Transplantation Research\",\"volume\":\"54 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Translational Medicine & Transplantation Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47363/jtmtr/2023(2)109\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Translational Medicine & Transplantation Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47363/jtmtr/2023(2)109","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Investigation of Regenerative Effects of Theranekron® and Misoprostol after Partial Hepatectomy in Rats
In the present study we were aimed to investigate/compare regenerative effects of Theranekron® (TC) and Misoprostol (MS) after Partial Hepatectomy (PH) in rats. This study was conducted in 38 rats, they were divided in to 5 groups and 7 days study periot. When considering biochemical and histopathological results; we were seen that after PH 7 days duration was not sufficient and also at least 10 days periot may be necessary. Although some literatures were reported about positive effects of TC and MS on epithelial growing, we have not seen that they have not any positive effect on liver regeneration. In the future -at different doses and durations- these may be found effective.
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