阿富汗脊柱结核:对喀布尔医院患者的2019 - 2020年研究

Farah Qaderi, Idriss Mashid, Latif Gachkar, Mosè Martellucci, Shohra Qaderi, Akihiko Ozaki, Alireza Haghbin Toutounchi, Afshin Taheriazam, Takanori Asakura, Hojat Gholipoor Talemi, Noria Mohammady, Minoosh Shabani
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摘要

背景结核病(TB)在许多低收入国家流行,其可影响1%-5%的活动性感染患者的脊柱。本研究报告了阿富汗喀布尔(一个资源非常有限的国家)收治的脊柱结核患者的临床特征。方法对2019年3月至2020年4月期间在阿富汗喀布尔三家主要转诊医院接受脊柱结核治疗的26例患者进行描述性研究。从患者的医疗记录中检索患者的社会人口学和临床细节、性别、年龄、感染部位、主诉、体征和症状。汇总统计数据采用SPSS version 20进行分析。获得了伊朗德黑兰Shahid Beheshti医学科学大学伦理委员会的伦理批准。结果连续收治26例脊柱结核患者。样本平均年龄38.2岁(SD 17.5),男性16例,女性10例。从症状出现到住院的中位时间为60天。最常用的诊断成像技术是磁共振成像(92.3%),其次是计算机断层扫描(7.7%)。大多数病变累及腰椎(61.4%),其次是胸腰椎(30.8%)。21例(80.8%)患者以背痛为最常见的症状,16例(61.5%)患者出现不同程度的神经功能障碍。截至出院日,患者无死亡病例。结论:本研究描述了阿富汗喀布尔脊柱结核患者的临床特征。必须加强预防策略,并提高对慢性背痛患者脊柱结核临床特征的健康认识,即使在没有结核病迹象的情况下。
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Spinal tuberculosis in Afghanistan: A 2019‐2020 study of patients in Kabul hospitals
Abstract Background Tuberculosis (TB) is endemic in many low‐income countries, which can affect the spine in 1%–5% of those with an active infection. This study reports the clinical characteristics of patients admitted for spinal TB in Kabul, Afghanistan, a country with very limited resources. Methods This was a descriptive study among 26 patients treated for spinal TB in three major referral hospitals in Kabul, Afghanistan, between March 2019 and April 2020. The sociodemographic and clinical details, gender, age, site of infection, presenting complaints, signs, and symptoms of the patients were retrieved from their medical records. Summary statistics were analyzed using SPSS version 20. Ethics approval was obtained from the ethics committee of Shahid Beheshti University of Medical Sciences in Tehran, Iran. Results Data were available for 26 patients with spinal TB admitted consecutively. The mean age of the sample was 38.2 years (SD 17.5), and there were 16 males and 10 females. Median time from symptom onset to hospital admission was 60 days. The most common diagnostic imaging technique used was magnetic resonance imaging (92.3%), followed by computed tomography (7.7%). The majority of the lesions involved the lumbar spine (61.4%), followed by the thoracolumbar spine (30.8%). Back pain was the most common manifestation in 21 patients (80.8%), and varying degrees of neurological impairment were found in 16 (61.5%) patients. There were no deaths among the patients up to the discharge date. Conclusions This study describes the clinical characteristics of spinal TB among patients in Kabul, Afghanistan. It is essential to strengthen preventive strategies and to improve health awareness about clinical features of spinal TB in patients with chronic back pain even in the absence of signs of TB.
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