{"title":"尿液结核LAM作为辅助肺结核诊断和随访治疗反应的工具","authors":"Sawang Saenghirunvattana, Thiti Sricharoenchai, Sirintip Sricharoenchai","doi":"10.31524/bkkmedj.2023.21.004","DOIUrl":null,"url":null,"abstract":"OBJECTIVES: To evaluate role of urine Tuberculosis Lipoarabinomannam (TB LAM) in making a diagnosis among human immunodeficiency virus (HIV) negative patients with pulmonary tuberculosis. MATERIALS AND METHODS: Sixty-six cases of HIV negative who were suspected of pulmonary tuberculosis were recruited, sputum examination of acid fast stain and culture, chest x-ray, urine TB LAM were sent, bronchoscopy and washing and biopsy were performed among 12 cases. RESULTS: Thirty-six patients were finally diagnosed as tuberculosis. The sensitivity of urine TB LAM was 66.7%, specificity was 90%. CONCLUSION: TB LAM should be used as an add-on to clinical judgement in combination with other tests. Keywords: urine TB LAM, pulmonary tuberculosis","PeriodicalId":92144,"journal":{"name":"The Bangkok medical journal","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Urine TB LAM as a Tool for Helping Diagnosis and Follow Up of Treatment Response of Pulmonary Tuberculosis\",\"authors\":\"Sawang Saenghirunvattana, Thiti Sricharoenchai, Sirintip Sricharoenchai\",\"doi\":\"10.31524/bkkmedj.2023.21.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"OBJECTIVES: To evaluate role of urine Tuberculosis Lipoarabinomannam (TB LAM) in making a diagnosis among human immunodeficiency virus (HIV) negative patients with pulmonary tuberculosis. MATERIALS AND METHODS: Sixty-six cases of HIV negative who were suspected of pulmonary tuberculosis were recruited, sputum examination of acid fast stain and culture, chest x-ray, urine TB LAM were sent, bronchoscopy and washing and biopsy were performed among 12 cases. RESULTS: Thirty-six patients were finally diagnosed as tuberculosis. The sensitivity of urine TB LAM was 66.7%, specificity was 90%. CONCLUSION: TB LAM should be used as an add-on to clinical judgement in combination with other tests. Keywords: urine TB LAM, pulmonary tuberculosis\",\"PeriodicalId\":92144,\"journal\":{\"name\":\"The Bangkok medical journal\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Bangkok medical journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31524/bkkmedj.2023.21.004\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Bangkok medical journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31524/bkkmedj.2023.21.004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Urine TB LAM as a Tool for Helping Diagnosis and Follow Up of Treatment Response of Pulmonary Tuberculosis
OBJECTIVES: To evaluate role of urine Tuberculosis Lipoarabinomannam (TB LAM) in making a diagnosis among human immunodeficiency virus (HIV) negative patients with pulmonary tuberculosis. MATERIALS AND METHODS: Sixty-six cases of HIV negative who were suspected of pulmonary tuberculosis were recruited, sputum examination of acid fast stain and culture, chest x-ray, urine TB LAM were sent, bronchoscopy and washing and biopsy were performed among 12 cases. RESULTS: Thirty-six patients were finally diagnosed as tuberculosis. The sensitivity of urine TB LAM was 66.7%, specificity was 90%. CONCLUSION: TB LAM should be used as an add-on to clinical judgement in combination with other tests. Keywords: urine TB LAM, pulmonary tuberculosis
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