[保存液中抗坏血酸对小型猪肝移植中血浆抗氧化电位的影响]。

I Popov, W Gäbel, W Lohse, G Lewin, E Richter, R von Baehr
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引用次数: 0

摘要

血浆的抗氧化电位(AP)是由其氧-来定义的。捕获能力。超氧自由基是在光化学系统中产生的,用鲁米诺化学发光法检测。在小型猪实验性肝移植制备阶段,外周血AP升高2倍。移植血循环1小时后AP升高20倍。在低温保存期间,抗坏血酸对器官的抗氧化防御消除了这些增加。讨论了所观察到的现象的可能机制和血浆AP测量的信息意义。
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[The effect of ascorbic acid in preservation solutions on the antioxidative potential of blood plasma during liver transplantation in miniature swine].

The antioxidative potential (AP) of blood plasma was defined for its O2-.-trapping capacity. The superoxide radicals were generated in a photochemical system and detected by luminol chemiluminescence. During the preparation phase of experimental liver transplantation on mini-pig the AP of peripheral blood increased twice. There is a 20-fold increase of AP one hour after the blood recirculation in transplant. An antioxidative defence of organ with ascorbic acid during the cold preservation period removed these increase. The possible mechanisms of the observed phenomena and the information significance of the AP measurement in blood plasma are discussed.

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