[结节病血浆转化酶与肾素的比较研究]。

I Hăulică, C Ionescu, V Roşca, T Mihăeseu, V Rusu, C Tănase-Galicescu, D Boişteanu
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引用次数: 0

摘要

本文对55例临床诊断为结节病等肺部疾病的患者进行了转化酶与血浆肾素的比较研究。尽管在皮质激素治疗后,转化酶在活动性结节病中表现出重要的增加,并倾向于正常状态,但在皮质激素治疗前后,血浆肾素的活性保持不变。所得结果与文献数据一致,证明了转化酶用量试验的实用性。他们还指出肺SRA可能参与血管和局部酶化学失衡,提示转换酶抑制剂可能与皮质激素治疗结节病有关。
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[A comparative study of plasma converting enzyme and renin in sarcoidosis].

The paper reports on a comparative study of the conversion enzyme and plasmatic renin performed on a group of 55 patients, with clinical diagnosis of sarcoidosis and other lung diseases. Whereas the conversion enzyme showed important increases in active sarcoidosis and a tendency to the normal state after treatment with corticoids, the activity of the plasmatic renin remained the same, both before and after corticotherapy. The result obtained prove the practical usefulness of the dosage test of the conversion enzyme, in agreement with the literature data. They also point to the possible participation of the pulmonary SRA in the vascular and local enzymatic-chemical imbalances, suggesting the possibility of associating the conversion enzyme inhibitors to the treatment of sarcoidosis with corticoids.

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