{"title":"老龄大鼠基底前脑、海马和新皮层神经传递改变的免疫和组织化学证据。","authors":"I Lolova, M Davidoff","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The distribution of choline acetyltransferase- and gamma-aminobutyric acid-immunoreactivity as well as acetylcholinesterase-, gamma-aminobutyrci acid-transaminase- and monoaminooxidase-positive structures in the basal forebrain, hippocampal formation and neocortex of young adult and aged rats was compared. The changes in the staining and density of the immuno- and histochemical positive nerve cells and fibers observed provide evidence for the involvement of different transmitters in normal ageing.</p>","PeriodicalId":75355,"journal":{"name":"Zeitschrift fur mikroskopisch-anatomische Forschung","volume":"103 6","pages":"840-54"},"PeriodicalIF":0.0000,"publicationDate":"1989-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Immuno- and histochemical evidence for changed neurotransmission in basal forebrain, hippocampal formation and neocortex of aged rats.\",\"authors\":\"I Lolova, M Davidoff\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The distribution of choline acetyltransferase- and gamma-aminobutyric acid-immunoreactivity as well as acetylcholinesterase-, gamma-aminobutyrci acid-transaminase- and monoaminooxidase-positive structures in the basal forebrain, hippocampal formation and neocortex of young adult and aged rats was compared. The changes in the staining and density of the immuno- and histochemical positive nerve cells and fibers observed provide evidence for the involvement of different transmitters in normal ageing.</p>\",\"PeriodicalId\":75355,\"journal\":{\"name\":\"Zeitschrift fur mikroskopisch-anatomische Forschung\",\"volume\":\"103 6\",\"pages\":\"840-54\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1989-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur mikroskopisch-anatomische Forschung\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur mikroskopisch-anatomische Forschung","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Immuno- and histochemical evidence for changed neurotransmission in basal forebrain, hippocampal formation and neocortex of aged rats.
The distribution of choline acetyltransferase- and gamma-aminobutyric acid-immunoreactivity as well as acetylcholinesterase-, gamma-aminobutyrci acid-transaminase- and monoaminooxidase-positive structures in the basal forebrain, hippocampal formation and neocortex of young adult and aged rats was compared. The changes in the staining and density of the immuno- and histochemical positive nerve cells and fibers observed provide evidence for the involvement of different transmitters in normal ageing.
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