[心肌疾病、心力衰竭和反应性结核样麻风病]。

Hansenologia internationalis Pub Date : 1989-12-01
D V Opromolla, R N Fleury
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引用次数: 0

摘要

一名60岁妇女因充血性心力衰竭、原发性高血压和腹胀入院。她的儿子报告说,她身上出现了红色的斑点,她正在接受氨苯砜治疗。七个月前皮肤损伤突然增多。在入院后的第11天,她经历了一次中风,进展为精神衰弱,并于第4天死亡。尸检证实CHF是由与恰加斯病相关的慢性心肌炎引起的。左心室顶区动脉瘤也被观察到导致血栓形成和全身栓塞伴脑和脾出血性梗死。脑部有水肿、脐突出和脑干出血性梗死。皮肤病变是由反应性结核样汉森病(RHT)引起的,病灶位于腋窝淋巴结、鼻咽粘膜和胫后神经。本文讨论了RHT的发病机制,与Ridley和Jopling的BT群的区别,以及RHT与Ridley报道的继发性结核样汉森病的可能关系。局灶性病变也被讨论到末梢神经干受累,这在这种形式的汉森氏病中是不常见的。
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[Myocardial disease, heart failure and reactional tuberculoid leprosy].

A 60-year-old woman was admitted with congestive heart failure, essential hypertension and abdominal distension. Her son reported that she appeared with red spots in the body and that she was under dapsone therapy. Seven months ago there was sudden increase of the skin lesions. In the 11th day after admission she underwent a stroke that progressed to decerebration and she expired on the fourth day. Autopsy confirmed CHF due to chronic myocarditis related to Chagas' disease. Aneurysm of the apical region of the left ventricular chamber was also observed leading to thrombosis and systemic embolism with brain and spleen hemorrhagic infarct. In the encephalous there was edema, uncus herniation and hemorrhagic infarct of the brain stem. The skin lesions were due to reactional tuberculoid hanseniasis (RHT) with focal lesions in axillary lymphnodes, nasopharyngeal mucosa and in the posterior tibial nerve. The pathogenesis of RHT is discussed as well as its differentiation with the BT group of Ridley and Jopling and its probably relationship with the secondary tuberculoid hanseniasis reported by Ridley. The focal lesions are also discussed with END to the involvement of a peripheral nerve trunk what is said to be uncommon in this form of Hansen's disease.

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Evolução do grau de incapacidade física e do escore olhos, mãos e pés em casos novos de hanseníase [Efficacy of multidrug therapy in treatment of paucibacillary leprosy patients--preliminary results]. [Prevention and treatment of physical disabilities in Hansen's disease in Brazil: study of specific professional risk for the disease]. [Myocardial disease, heart failure and reactional tuberculoid leprosy]. Histogenic differentiation of polar tuberculoid granuloma and the "benign" or "malignant" behaviour of hanseniasis.
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