血浆细胞在肾移植排斥反应中的意义。

Morphologiai es igazsagugyi orvosi szemle Pub Date : 1989-10-01

T Nadasdy, T Krenács, K Kalmár-Nagy, E Csajbók, K Boda

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引用次数: 0

摘要

作者采用免疫组化方法对移植肾排斥反应、不同排斥反应、环孢素a肾毒性和慢性间质性肾炎患者浆细胞免疫球蛋白含量进行了比较。到目前为止，大多数浆细胞发生在慢性排斥反应中，含有80%以上的IgG。而慢性间质性肾炎绝大多数浆细胞IgG阳性。可能在慢性排斥反应中，除了细胞免疫机制外，一种特殊的、继发性的体液免疫反应也起着重要的作用。

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[Significance of plasma cells in the rejection of kidney grafts].

Authors studied with immunohistochemical methods the immunoglobulin content of plasma cells during the rejection of renal grafts, in different rejections, in Cyclosporin-A nephro-toxicity and in chronic interstitial nephritis, as a comparison. By far the most plasma cells occurred in chronic rejection, containing more than 80% IgG. Whereas great majority of plasma cells were IgG positive in chronic interstitial nephritis. Probably, in chronic rejection a special, secondary type humoral immune reaction has a significant role in addition to cellular immune mechanisms.

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Morphologiai es igazsagugyi orvosi szemle

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