[非洲恶性疟原虫耐药性和磺胺多辛-乙胺嘧啶]。

Bulletin de la Societe de pathologie exotique et de ses filiales Pub Date : 1989-01-01

J R Randriamanjaka, J Le Bras, G Charmot, J P Coulaud

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引用次数: 0

摘要

自1985年美国发生严重事故后，磺胺多辛-乙胺嘧啶组合就没有被推荐用于预防疟疾。然而，这种药物值得考虑用于治疗，因为它比甲氟喹更便宜，副作用更少，而且可以避免使用甲氟喹。应对输入法国的病例进行恶性疟原虫对范西达耐药性的研究，以确定该药的适应性利用。这对热带非洲来说将是一个明显的优势。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Plasmodium falciparum drug resistance and sulfadoxine-pyrimethamine in Africa].

The sulfadoxine-pyrimethamine combination has not been recommended for the prophylaxis of malaria since 1985 following serious accidents in the USA. However, this drug is worth considering for treatment since it has the advantage over mefloquine of being cheaper, having fewer side effects and it avoids using mefloquine. A study of Plasmodium falciparum resistance to Fansidar should be carried out on cases imported to France to determine an adapted utilisation of this drug. This would be an appreciable advantage for tropical Africa.

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Bulletin de la Societe de pathologie exotique et de ses filiales

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