亚麻籽蛋白质组的抗癌特性

IF 4 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY Proteomes Pub Date : 2023-11-16 DOI:10.3390/proteomes11040037
Yulia Merkher, Elizaveta Kontareva, Anastasia Alexandrova, Rajesha Javaraiah, Margarita Pustovalova, Sergey Leonov
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引用次数: 0

摘要

亚麻籽被认为是营养物质和生物活性化合物的宝贵来源,包括具有各种健康益处的蛋白质。近年来,研究表明亚麻籽蛋白,包括白蛋白、球蛋白、麸质蛋白和蛋白,具有抗癌特性。这些特性归因于它们能够抑制癌细胞增殖,诱导细胞凋亡,干扰癌细胞信号通路,最终导致抑制转移。此外,据报道,亚麻籽蛋白可以调节癌细胞的机械生物学,导致细胞行为的改变,减少癌细胞的迁移和侵袭。本文综述了亚麻籽蛋白的抗癌特性,重点介绍了亚麻籽蛋白在癌症治疗中的潜在应用。此外,它强调需要进一步研究,以充分确定亚麻籽蛋白在癌症治疗中的潜力。
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Anti-Cancer Properties of Flaxseed Proteome.

Flaxseed has been recognized as a valuable source of nutrients and bioactive compounds, including proteins that possess various health benefits. In recent years, studies have shown that flaxseed proteins, including albumins, globulins, glutelin, and prolamins, possess anti-cancer properties. These properties are attributed to their ability to inhibit cancer cell proliferation, induce apoptosis, and interfere with cancer cell signaling pathways, ultimately leading to the inhibition of metastasis. Moreover, flaxseed proteins have been reported to modulate cancer cell mechanobiology, leading to changes in cell behavior and reduced cancer cell migration and invasion. This review provides an overview of the anti-cancer properties of flaxseed proteins, with a focus on their potential use in cancer treatment. Additionally, it highlights the need for further research to fully establish the potential of flaxseed proteins in cancer therapy.

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来源期刊
Proteomes
Proteomes Biochemistry, Genetics and Molecular Biology-Clinical Biochemistry
CiteScore
6.50
自引率
3.00%
发文量
37
审稿时长
11 weeks
期刊介绍: Proteomes (ISSN 2227-7382) is an open access, peer reviewed journal on all aspects of proteome science. Proteomes covers the multi-disciplinary topics of structural and functional biology, protein chemistry, cell biology, methodology used for protein analysis, including mass spectrometry, protein arrays, bioinformatics, HTS assays, etc. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. Therefore, there is no restriction on the length of papers. Scope: -whole proteome analysis of any organism -disease/pharmaceutical studies -comparative proteomics -protein-ligand/protein interactions -structure/functional proteomics -gene expression -methodology -bioinformatics -applications of proteomics
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