卡咪唑治疗后急性亚块状胆汁淤积性肝炎。一个新病例的报告和文献综述]。

D Moreno Sánchez, J Medina Asensio, F Colina Ruiz-Delgado, R Campos Cantero, L Crespo Rincón, A Belda Serna
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引用次数: 0

摘要

Carbimazole是一种硫咪唑类抗甲状腺药物,可引起不可预测的肝脏改变,可能是由过敏引起的。我们描述的情况下,甲状腺机能亢进的妇女谁遭受急性次大规模胆汁淤积性肝炎在治疗过程中与这种药物。我们还回顾了文献中报道的其他7例卡咪唑肝毒性病例。
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[Acute submassive cholestatic hepatitis after treatment with carbimazole. Presentation of a new case and review of the literature].

Carbimazole, an antithyroid agent of the thioimidazole group, can induce unpredictable liver alterations, presumably by hypersensitivity. We describe the case of a hyperthyroid woman who suffered acute submassive cholestatic hepatitis in the course of treatment with this drug. We also review the other seven cases of carbimazole hepatotoxicity previously communicated in the literature.

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