在ICU如何监测谵妄及其重要性

Daniel Krahne, Anja Heymann, Claudia Spies
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引用次数: 14

摘要

谵妄是一种严重的大脑器质性功能障碍,伴有注意力和认知能力下降。它的特点是急性发作,有波动的倾向,意识受损,意识清晰度降低。此外,它还表现为注意力集中、维持或转移注意力的能力下降,认知能力发生变化或出现幻觉的知觉障碍。在65岁以上的住院患者中,高达20%的患者受到影响,在重症监护环境中,这一比例高达80%。一旦出现谵妄,就与认知能力差、痴呆和费用增加有关。谵妄是死亡率和重症监护病房(ICU)和住院时间延长的独立预测因子。为了早期诊断谵妄,日常监测是必要的。谵妄的症状和原因各不相同。应使用特殊的量表来评估谵妄。“谵妄检测量表”(DDS)和“神志不清评定法”(CAM-ICU)都是ICU患者谵妄的有效且可靠的测量方法。必须排除任何可能的一般医疗状况。本文概述了严密监测的重要性,以实现最佳治疗,并避免患者出现相关并发症,如在ICU和医院的住院时间延长、死亡率增加、认知预后差和费用增加。
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How to monitor delirium in the ICU and why it is important

Delirium is a severe organic dysfunction of the brain with a decline in attention and cognition. It is characterized by an acute onset with a tendency to fluctuate and impaired consciousness with reduced clarity of awareness. Furthermore it is designated by a reduced ability to focus, sustain, or shift attention and a change in cognition or a perceptual disturbance with hallucinations.

Up to 20% of hospitalized patients older than 65 years are affected, in an intensive care setting reports go up to 80%. Once delirium developed, it is associated with poor cognitive outcome, dementia and increased costs. Delirium is an independent predictor of mortality and prolonged stay in the intensive care unit (ICU) and hospital.

For early diagnosis of delirium, monitoring is required in daily routine. Symptoms of and reasons for delirium are very variable. The application of special scales to assess delirium should be performed. The “Delirium Detection Scale” (DDS) and the “Confusion Assessment Method” (CAM-ICU) are both validated and reliable measurements for delirium in ICU patients. Any possible general medical condition must be excluded.

This overview article is to demonstrate the importance of a tight monitoring to enable optimal treatment and to save patients from associated complications like prolonged stay in ICU and hospital, increased mortality, poor cognitive outcome and increased costs.

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