纳米颗粒作为靶向递送系统治疗肺癌的综述。

IF 2.6 4区 医学 Q3 CHEMISTRY, MEDICINAL Anti-cancer agents in medicinal chemistry Pub Date : 2024-01-01 DOI:10.2174/0118715206257442231109202235
Twinkle Gupta, Avinash Varanwal, Priyanshu Nema, Sakshi Soni, Arun Kumar Iyer, Ratnesh Das, Vandana Soni, Sushil Kumar Kashaw
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引用次数: 0

摘要

第二常见的癌症是影响人类的肺癌。肺癌的治疗有许多手术和非手术治疗,包括放疗、化疗和光动力治疗。然而,大部分的这些程序是昂贵的,困难的,和对病人的敌意。化疗的特点是肿瘤靶向性不足,药物溶解度低,药物转运到肿瘤部位不足。为了解决与化疗相关的问题,人们正在努力开发和研究各种类型的纳米颗粒,包括有机的和无机的,用于治疗肺癌。本文综述了活性靶向肺癌纳米药物递送系统治疗的研究进展,特别强调了受体或靶点。本研究的发现有望帮助生物医学研究人员利用纳米颗粒作为肺癌治疗的创新工具,为输送药物和可靠的固体配体提供新的方法。
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A Comprehensive Review on Nanoparticles as a Targeted Delivery System for the Treatment of Lung Cancer.

The second most common type of cancer is lung cancer, impacting the human population. Lung cancer is treated with a number of surgical and non-surgical therapies, including radiation, chemotherapy, and photodynamic treatment. However, the bulk of these procedures are costly, difficult, and hostile to patients. Chemotherapy is distinguished by inadequate tumour targeting, low drug solubility, and insufficient drug transport to the tumour site. In order to deal with the issues related to chemotherapy, extensive efforts are underway to develop and investigate various types of nanoparticles, both organic and inorganic, for the treatment of lung cancer. The subject of this review is the advancements in research pertaining to active targeted lung cancer nano-drug delivery systems treatment, with a specific emphasis on receptors or targets. The findings of this study are expected to assist biomedical researchers in utilizing nanoparticles (NPs) as innovative tools for lung cancer treatment, offering new methods for delivering drugs and reliable solid ligands.

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来源期刊
Anti-cancer agents in medicinal chemistry
Anti-cancer agents in medicinal chemistry ONCOLOGY-CHEMISTRY, MEDICINAL
CiteScore
5.10
自引率
3.60%
发文量
323
审稿时长
4-8 weeks
期刊介绍: Formerly: Current Medicinal Chemistry - Anti-Cancer Agents. Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents. Each issue contains a series of timely in-depth reviews and guest edited issues written by leaders in the field covering a range of current topics in cancer medicinal chemistry. The journal only considers high quality research papers for publication. Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.
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