以前向散射为主的薄骨层在组织幻象中的角度依赖光散射。

IF 2 3区 物理与天体物理 Q3 BIOCHEMICAL RESEARCH METHODS Journal of Biophotonics Pub Date : 2023-11-29 DOI:10.1002/jbio.202300358
Tom Witke, Eduard Kuhn, Fabian Teichert, Christian Goßler, Ulrich Theodor Schwarz, Angela Thränhardt
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引用次数: 0

摘要

耳蜗是颞骨中人类听觉系统的重要组成部分。耳蜗的损伤继续对环境刺激的感觉接收产生重大损害。为了改善这种缺陷,光学人工耳蜗形成了一种新的研究途径。这种方法的先决条件是了解光的传播、散射、反射和吸收是如何在耳蜗内发生的。我们提出了一种通过模拟骨光学行为的模拟材料和蒙特卡罗模拟来研究人耳蜗内光分布的方法。计算散射后的角分布需要一个相函数。通常近似函数如Henyey-Greenstein,两项Henyey-Greenstein或Legendre多项式分解被用作相函数。另一种方法是精确地计算每个散射事件的米氏分布。该方法能更好地拟合本工作中测量的数据。这篇文章受版权保护。版权所有。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Angle-dependent light scattering in tissue phantoms for the case of thin bone layers with predominant forward scattering

The cochlea forms a key element of the human auditory system in the temporal bone. Damage to the cochlea continues to produce significant impairment for sensory reception of environmental stimuli. To improve this impairment, the optical cochlear implant forms a new research approach. A prerequisite for this method is to understand how light propagation, as well as scattering, reflection, and absorption, takes place within the cochlea. We offer a method to study the light distribution in the human cochlea through phantom materials which have the objective to mimic the optical behavior of bone and Monte-Carlo simulations. The calculation of an angular distribution after scattering requires a phase function. Often approximate functions like Henyey–Greenstein, two-term Henyey–Greenstein or Legendre polynomial decompositions are used as phase function. An alternative is to exactly calculate a Mie distribution for each scattering event. This method provides a better fit to the data measured in this work.

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来源期刊
Journal of Biophotonics
Journal of Biophotonics 生物-生化研究方法
CiteScore
5.70
自引率
7.10%
发文量
248
审稿时长
1 months
期刊介绍: The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.
期刊最新文献
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