胃肠内窥镜介入功能诊断:将内窥镜套件中的诊断和治疗工具与功能性管腔成像探头相结合

IF 4 3区 医学 Q1 PHARMACOLOGY & PHARMACY Current Opinion in Pharmacology Pub Date : 2023-11-28 DOI:10.1016/j.coph.2023.102414
Zuzana Vackova , Ian Levenfus , Daniel Pohl
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引用次数: 0

摘要

随着胃肠功能检测技术的进步,人们要求在高分辨率测压法之外,对食管生理和病理生理进行更全面的检查。一种基于阻抗平面测量的新型介入技术——功能性管腔成像探针(FLIP),可以在腔内测量中空器官的扩张性和顺应性。EndoFLIP使用球囊导管测量直径和扩张压力,计算不同器官(主要是食道、胃、肛肠区域)的横截面积和扩张率,可用于各种适应症(诊断、治疗前和治疗后评估),目前是临床上模棱两可病例的辅助工具。EsoFLIP是一种治疗性的变体,使用更硬的球囊导管进行扩张。简化从诊断到治疗的临床过程的趋势趋向于将诊断和治疗干预相结合的一次会议程序。在特定的情况下,如贲门失弛缓症或胃轻瘫,EndoFLIP和EsoFLIP手术的组合可能是有用的。这篇叙述性综述的目的是介绍FLIP的临床应用及其在联合诊断和治疗过程中的潜在益处。
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Interventional functional diagnostics in gastrointestinal endoscopy: Combining diagnostic and therapeutic tools in the endoscopy suite with the functional lumen imaging probe

With technical progress of gastrointestinal functional testing, there has been a demand for more comprehensive examination of esophageal physiology and pathophysiology beyond high-resolution manometry. A new interventional technology based on impedance planimetry, the functional lumen imaging probe (FLIP), enables intraluminal measurement of distensibility and compliance of hollow organs. EndoFLIP uses balloon catheters to measure diameter and distension pressure to calculate cross-sectional area and distensibility in different organs (mostly esophagus, stomach, anorectal region) and can be used in wide variety of indications (diagnostics, pre- and post-treatment evaluation) and currently serves as a helpful adjunctive tool in ambiguous clinical cases. EsoFLIP is a therapeutic variation that uses a stiffer balloon catheter allowing for dilation. The trend to simplify the clinical process from diagnosis to treatment tends to a one-session procedure combining diagnostics and therapeutic interventions. In specified conditions like e.g. achalasia or gastroparesis, a combination of EndoFLIP and EsoFLIP procedures may therefore be useful. The aim of this narrative review is to introduce the clinical use of FLIP and its potential benefit in combined diagnostic-therapeutic procedures.

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来源期刊
CiteScore
8.80
自引率
2.50%
发文量
131
审稿时长
4-8 weeks
期刊介绍: Current Opinion in Pharmacology (COPHAR) publishes authoritative, comprehensive, and systematic reviews. COPHAR helps specialists keep up to date with a clear and readable synthesis on current advances in pharmacology and drug discovery. Expert authors annotate the most interesting papers from the expanding volume of information published today, saving valuable time and giving the reader insight on areas of importance.
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