β-取代乙烯基膦酸盐的合成、合成兴趣和生物活性

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-02-01 DOI:10.1080/10426507.2023.2281472

Cécile Garzon , Mireille Attolini , Michel Maffei

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摘要

β-取代的乙烯基膦酸盐构成了一类原始的有机磷试剂，其中一些化合物具有吸引人的生物学特性。这篇评论举例说明并讨论了……

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Synthesis, synthetic interests, and biological activities of β-substituted vinylphosphonates

β-Substituted vinylphosphonates constitute an original class of organophosphorus reagents of which several compounds exhibit attractive biological properties. The review exemplifies and discusses the different synthetic methods described for their synthesis, which involve well known reactions, but also more specifically designed methods. In addition, the uses as synthetic intermediates as well as the therapeutic uses of the title compounds are also summarized.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.