调查类风湿关节炎患者颈椎不稳的患病率

IF 0.7 Q4 CLINICAL NEUROLOGY Egyptian journal of neurosurgery Pub Date : 2023-11-20 DOI:10.1186/s41984-023-00241-w
Amir Rezakhah, Andrew J. Kobets, Faezeh Emami Sigaroudi, Mohammad Amin Habibi, Rahim Derakhshesh, Naghmeh Javanshir Rezaei, Seyed Ahmad Naseri Alavi
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引用次数: 0

摘要

类风湿性关节炎(RA)是一种慢性、进行性、全身性疾病,广泛影响结缔组织,尤其是滑膜关节。本研究的目的是调查诊断为RA的患者中颈椎不稳定的患病率。人口普查选择了50名到乌尔米亚伊玛目霍梅尼医院就诊的类风湿关节炎患者。记录病史后,在静态、屈曲和伸展侧位角度拍摄颈部x线片。50例患者中,男性11例(22%),女性39例(78%)。平均病程为5.63±5.21年。AADI正常43例(86%),动态AADI异常5例(10%),静态AADI异常2例(4%)。在研究的患者中未发现颅底内陷不稳。AADI正常与异常病例的性别差异无统计学意义。正常AADI患者中有40例(93%)服药,异常AADI患者中有4例(57.1%)服药,3例(42.9%)未服药。在药物使用方面,AADI正常病例与异常病例有显著差异。在我们的研究中,50例患者中有7例AADI异常,其中2例为静态AADI异常,说明颈椎不稳定的恶化。该研究还发现,未接受DMARDS治疗的患者更有可能出现颈椎不稳定。
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Investigating the prevalence of cervical spine instability in patients with rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic, progressive, and systemic disease that broadly affects connective tissues, especially synovial joints. The aim of this study was to investigate the prevalence of cervical spine instability in patients diagnosed with RA. Fifty patients with rheumatoid arthritis referred to Imam Khomeini Hospital in Urmia were selected by the census. After taking a history, the neck X-ray was taken from the lateral view in static, flexion, and extension. Among 50 patients, 11 were male (22%) and 39 were female (78%). The average disease duration period was 5.63 ± 5.21 years. 43 patients (86%) had normal AADI, 5 patients (10%) had abnormal dynamic AADI, and 2 patients (4%) had abnormal AADI static. Basilar invagination instability was not found in the studied patients. There was no significant difference in terms of gender between normal and abnormal cases of AADI. Among normal AADI cases, 40 cases (93%) were taking drugs and among abnormal AADI cases, 4 cases (57.1%) were taking drugs and 3 patients (42.9%) were not receiving drug treatment. There is a significant difference between normal and abnormal cases of AADI in terms of drug use. In our study, 7 cases of abnormal AADI were found among 50 patients, of which 2 had abnormal static AADI, which indicates the worsening of cervical spine instability. The study also found that those not treated with DMARDS were more likely to have cervical spine instability.
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