影响伊朗南部 COVID-19 住院病人死亡的风险因素

Ehsan Goroei Sardu, Fatemeh Rezabeigi Davarani, Bahareh Kermani, R. Faryabi, Shiva Kargar, Shamim Tashakori, S. Daneshi
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摘要

背景:确定COVID-19感染导致死亡的有效因素是全球最令人担忧的问题之一。本研究旨在调查导致COVID-19患者死亡的危险因素频率。方法:对2019年伊玛目霍梅尼医院收治的150例新冠肺炎确诊病例进行回顾性描述性研究。采用普查方法纳入患者。提取所需信息并记录在研究人员的检查表中;其中包括患者的人口统计学和社会特征(年龄、性别、吸烟和吸食鸦片)、潜在疾病、检测结果(白细胞减少、白细胞增多、中性粒细胞减少、白蛋白降低、肌酐升高、ALT、AST、LDH和CRP)以及RT-PCR检测。研究人员使用独立样本t检验和SPSS-V22卡方分析数据。结果:患者平均年龄72.19±15.97岁。死于COVID-19的大多数是男性。药物使用与COVID-19患者死亡有统计学意义(p值<0.05)。超重组确诊患者的平均体重指数(BMI)为31.14±7.08 kg/m2 (p值<0.001)。此外,危险因素CRP、ALB、AST、ALT、Cr、lym、Neut、WBC与COVID-19患者不可避免死亡之间存在显著相关性(p值<0.001)。在基础疾病方面,大多数终末期患者有糖尿病、肺部和肾脏疾病(p值<0.001)。结论:老年、男性、高BMI、血压、CRP、AST、ALT、Cr、lym、Neut、WBC升高、ALB降低是导致COVID-19患者死亡的危险因素。
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Risk Factors Affecting the Death of Hospitalized Patients with COVID-19 in the South of Iran
Background: Identifying effective factors in death caused by the infection of COVID-19 is one of the most worrisome issues in the globe. This study aims to investigate the frequency of risk factors leading to death in patients with COVID-19. Methods: This was a retrospective descriptive study done on 150 confirmed cases of  COVID-19 in Imam Khomeini Hospital in Jiroft in 2019. Patients were included in the study by census method. The required information was extracted and recorded in the researcher's checklist; which included demographic and social characteristics of patients (age, gender, smoking, and opium consumption), underlying disease,test results (leukopenia, leukocytosis, neutropenia, decrease in albumin, increase in creatinine, ALT, AST, LDH and CRP), and the RT-PCR test.,. The researchers analyzed data using independent sample t-test, and chi-square by SPSS-V22.  Results: The mean age of the patients was 72.19 ± 15.97. Most of those who died with COVID-19 were men. There was a statistically significant relationship between the use of drugs and the death of patients with COVID-19(P-value<0.05). The average body mass index (BMI) of the confirmed patients was 31.14 ± 7.08 kg/m2 in the overweight group (P-value<0.001). Moreover, there was a significant relationship between the risk factors CRP, ALB, AST, ALT, Cr, lym, Neut, WBC and inevitable death in patients with COVID-19(P-Value<0.001). Regarding underlying diseases, diabetes, lung, and kidney diseases have been observed in most terminal patients (P-value<0.001). Conclusion: Old age, male gender, high BMI, blood pressure, increased factors of CRP, AST, ALT, Cr, lym, Neut, WBC, and decreased ALB are among the risk factors leading to death in COVID-19 patients.  
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