基于数字手臂的癌症电热治疗技术建模与分析

Jing Xu, Man Zhang, Jiang-ming Kuang, Yuping Qin, Shuang Zhang
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Furthermore, the patent offers a theoretical foundation for exploring\nthe distribution of electrical signals and the associated heat in arm muscles, ensuring accurate\ntreatment.\n\n\n\nTo enable subsequent experimental validation, this patent integrates human\nanatomy and histological structure theory. The arm's geometric structure was derived from\nsegmentation, reconstruction, and substantiation based on a digital human image dataset. Using\nthe COMSOL Multiphysics 5.5 software, a semi-detailed finite element model was developed for\nthe numerical simulation of electrothermotherapy. 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引用次数: 0

摘要

肌内血管瘤(IMH)是一种位于横纹肌的弥漫性血管瘤,由于其罕见而常被忽视。肌内血管瘤(IMH)是一种位于横纹肌的弥漫性生长血管瘤,由于其罕见而常被忽视。本专利涉及电针与电热疗法的结合。通过将电信号引入电针系统,产生电磁热。这种热量导致肿瘤细胞的电解和热破坏,使有针对性和精确的癌症治疗成为可能。此外,该专利为探索手臂肌肉中电信号和相关热量的分布提供了理论基础,确保了准确的治疗。为了便于后续的实验验证,本专利整合了人体解剖学和组织学结构理论。在数字人体图像数据集的基础上,通过分割、重建和实证得到手臂的几何结构。利用COMSOL Multiphysics 5.5软件,建立了电热疗数值模拟的半详细有限元模型。在时域设置中,引入1 MHz和22 V的载波信号来评估电信号的分布和手臂肌肉中的相关热量。电信号、电磁热和组织坏死主要集中在外露电针针尖10mm以内的非球面区域,针尖处的最高耦合温度可达250℃。时域分析表明,耦合温度可在1分钟内升高,足以导致组织完全损伤,在同一时间内组织坏死率达到100%。随着时间的推移,耦合温度继续升高,但增量是适度的。5分钟后,温度变化可忽略不计,一旦组织坏死率达到100%,则保持一致。在利用电热疗法的精密肿瘤治疗系统中,注射电信号的大小、电针针尖的位置、治疗时间等因素对治疗的准确性起着至关重要的作用。该模型从空间和时间两个角度探讨了电针电热治疗肌肉血管瘤的效果。为精密电热治疗癌症提供了理论基础。在采用电热疗法的肿瘤精准治疗系统中,注射电信号的大小、电针针尖的位置和治疗时间都对精准治疗有显著影响。利用该模型从空间和时间两个方面对电针电热治疗肌肉内血管瘤进行分析,为癌症的精准电热治疗提供理论依据
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Modeling and Analysis of Cancer Electrothermic Therapy Technique Based on a Digital Arm
Intramuscular hemangioma (IMH) is a diffuse growth hemangioma located in the striated muscle, which is often overlooked due to its rarity. Intramuscular hemangioma (IMH) is a diffuse growth hemangioma located in the striated muscle, which is often overlooked due to its rarity. This patent pertains to the integration of electroacupuncture with electrothermotherapy. By introducing electrical signals into the electroacupuncture system, electromagnetic heat is produced. This heat leads to the electrolysis and thermal destruction of tumor cells, enabling targeted and precise cancer treatment. Furthermore, the patent offers a theoretical foundation for exploring the distribution of electrical signals and the associated heat in arm muscles, ensuring accurate treatment. To enable subsequent experimental validation, this patent integrates human anatomy and histological structure theory. The arm's geometric structure was derived from segmentation, reconstruction, and substantiation based on a digital human image dataset. Using the COMSOL Multiphysics 5.5 software, a semi-detailed finite element model was developed for the numerical simulation of electrothermotherapy. Within a time domain setting, a carrier signal of 1 MHz and 22 V was introduced to assess the distribution of electrical signals and the associated heat in the arm muscle. Electrical signals, electromagnetic heat, and tissue necrosis primarily concentrate in a spherical region within 10 mm of the exposed electroacupuncture tip, with the maximum coupling temperature reaching 250 °C at the tip. Time domain analysis revealed that the coupling temperature can rise within 1 min, sufficiently to cause complete tissue damage, with the tissue necrosis ratio reaching 100% in the same timeframe. While the coupling temperature continues to rise over time, the increment is modest. After 5 min, there is negligible temperature change, and once the tissue necrosis ratio reaches 100%, it remains consistent. In the precision tumor treatment system utilizing electrothermotherapy, factors, such as the magnitude of the injected electrical signal, placement of the electroacupuncture tip, and treatment duration play a crucial role in the treatment's accuracy. This model delves into the treatment of intramuscular hemangiomas using electroacupuncture electrothermotherapy from two perspectives: spatial and temporal domains. It provides a theoretical foundation for precise electrothermotherapy in cancer treatment. In the precise tumor treatment system with electrothermotherapy, the size of the injected electrical signal, the position of the electroacupuncture tip and the treatment duration all have a significant impact on the precise treatment. This model is used to analyzes the treatment of intramuscular hemangiomas with electroacupuncture electrothermotherapy from two aspects: spatial and temporal domains, providing a theoretical basis for the precise electrothermotherapy for cancer. null
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Recent Patents on Engineering
Recent Patents on Engineering Engineering-Engineering (all)
CiteScore
1.40
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发文量
100
期刊介绍: Recent Patents on Engineering publishes review articles by experts on recent patents in the major fields of engineering. A selection of important and recent patents on engineering is also included in the journal. The journal is essential reading for all researchers involved in engineering sciences.
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Current Status of Research on Fill Mining Systems Overview of Patents on Diamond Polishing Apparatus Evaluation of Land Subsidence Susceptibility in Kunming Basin Based on Remote Sensing Interpretation and Convolutional Neural Network Development and Prospects of Lander Vibration-Damping Structures Recent Patents on Closed Coal Storage Systems and Research of Similar Experimental
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