预防和治疗头颈部癌症急性放射性皮炎的光生物调节疗法:病例系列

Barbara Tamires Cruz Aires , Rayenne Augusta Mota Ferreira , Jean Carlos Serra Costa , Ceci Nunes Carvalho , Meire Coelho Ferreira , Cyrene Piazera Silva Costa
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引用次数: 0

摘要

目的评价光生物调节治疗(PBMT)对头颈癌患者放射性皮炎的预防作用,并根据急性放射性皮炎(ARD)的不同级别描述不同能量剂量的低功率激光治疗方案。方法和材料这是一项病例系列研究,对2021年1月至2022年2月期间在圣保罗o Luiz Jabaquara医院接受放射治疗期间进行光生物调节以预防和治疗ARD的15例头颈癌患者的医疗记录进行了评估。所获得的数据以描述性的方式组织起来。结果在符合研究条件的病历中,有3例因患者未接受PBMT而被丢弃。这三人发展为III级放射性皮炎,放疗治疗中断。在放射治疗期间接受光生物调节治疗的样本中,50%发生放射性皮炎。25%表现为I级放射性皮炎,25%表现为III级放射性皮炎。然而,只有1%的样本因放射性皮炎而中断放射治疗。结论光生物调节是一种安全有效的治疗放射性皮炎的方法,但需要更多的研究来建立一个PBMT方案。
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Photobiomodulation therapy for the prevention and treatment of acute radiation dermatitis in head and neck cancer: A case series

Objective

to evaluate the effects of photobiomodulation therapy (PBMT) in the prevention of radiodermatitis in patients with head and neck cancer and to describes a protocol for the use of low-power laser with different energy doses according to the grades of acute radiation dermatitis (ARD).

Methods and materials

This is a case series study and were evaluated the medical records of 15 patients with head and neck cancer who underwent photobiomodulation for prevention and\or treatment of ARD during radiotherapy treatment at São Luiz Jabaquara Hospital in São Paulo, from January 2021 to February 2022. The data obtained were organized in a descriptive way.

Results

Of the medical records eligible for the study, three were discarded because the patients did not undergo PBMT. These three evolved to grade III radiodermatitis and radiotherapy treatment was interrupted. Among sample receiving photobiomodulation therapy during radiotherapy treatment, 50 % developed radiodermatitis. 25 % presented grade I radiodermatitis and 25 % developed grade III radiodermatitis. However, only 1 % of the sample had its radiotherapy treatment interrupted due to radiodermatitis.

Conclusion

Photobiomodulation is a safe and effective alternative in the management of radiodermatitis, but more studies are needed to establish a PBMT protocol.

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