毛细管区带电泳:环境监测微型化的机遇与挑战

IF 5.4 Q1 CHEMISTRY, ANALYTICAL Sensing and Bio-Sensing Research Pub Date : 2023-12-15 DOI:10.1016/j.sbsr.2023.100617
Swapna A. Jaywant , Harshpreet Singh , Khalid Mahmood Arif
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引用次数: 0

摘要

经过十年的研究、开发和仪器商业化,毛细管电泳(CE)已经牢固地确立了自己作为一种公认的分析技术。CE是一种根据电荷和大小来分离带电物质的分离方法。在环境科学领域,由于其简单、高效、价格合理和紧凑的设计,CE仪器已成为理想的选择。此外,CE的设备要求很简单,使其非常适合易于小型化。这篇综述提供了CE技术的最新进展的全面概述,重点是其小型化。研究了便携式CE和基于微芯片的CE,探讨了它们的结构特点、优点和局限性。此外,它还研究了一种模块化方法,将所有基本组件整合到一块电路板上,为微型毛细管电泳领域的创新可能性提供了一个整体的视角。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Capillary zone electrophoresis: Opportunities and challenges in miniaturization for environmental monitoring

After a decade of research, development, and instrument commercialization, capillary electrophoresis (CE) has firmly established itself as a recognized analytical technique. CE is a separation method that segregates charged species based on their charge and size. In the field of environmental science, CE instruments have emerged as an ideal choice due to their simplicity, efficiency, affordability, and compact design. Furthermore, CE's equipment requirements are straightforward, making it well-suited for easy miniaturization. This review provides a comprehensive overview of the latest advancements in the CE technology, with a focus on its miniaturization. It delves into portable CE and microchip-based CE, exploring their structural characteristics, advantages, and limitations. Additionally, it investigates a modular approach that consolidates all essential components onto a single board, offering a holistic perspective on the innovative possibilities within the realm of miniature capillary electrophoresis.

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来源期刊
Sensing and Bio-Sensing Research
Sensing and Bio-Sensing Research Engineering-Electrical and Electronic Engineering
CiteScore
10.70
自引率
3.80%
发文量
68
审稿时长
87 days
期刊介绍: Sensing and Bio-Sensing Research is an open access journal dedicated to the research, design, development, and application of bio-sensing and sensing technologies. The editors will accept research papers, reviews, field trials, and validation studies that are of significant relevance. These submissions should describe new concepts, enhance understanding of the field, or offer insights into the practical application, manufacturing, and commercialization of bio-sensing and sensing technologies. The journal covers a wide range of topics, including sensing principles and mechanisms, new materials development for transducers and recognition components, fabrication technology, and various types of sensors such as optical, electrochemical, mass-sensitive, gas, biosensors, and more. It also includes environmental, process control, and biomedical applications, signal processing, chemometrics, optoelectronic, mechanical, thermal, and magnetic sensors, as well as interface electronics. Additionally, it covers sensor systems and applications, µTAS (Micro Total Analysis Systems), development of solid-state devices for transducing physical signals, and analytical devices incorporating biological materials.
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