ECMO 在肝移植受者中的应用

IF 3.6 2区 医学 Q2 IMMUNOLOGY Transplantation Reviews Pub Date : 2023-12-13 DOI:10.1016/j.trre.2023.100816
Yue Qiu , Ibtesam Hilmi
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引用次数: 0

摘要

体外膜氧合(ECMO)已成为维持呼吸和心脏功能的重要工具,当传统的方法已经失败。它在处理肝移植(LT)期间急性肺和心脏挑战中的功能已显著扩大。虽然ECMO最初被视为急性术中或移植后并发症的抢救策略,但其应用现在也包括肝移植前阶段。我们的综述旨在全面总结ECMO在肝移植受者术前和围手术期应用的研究和具体病例。通过评估已发表的文献,我们讨论了具体的适应症,所采用的ECMO类型,其结果,以及在LT期间应用ECMO的独特挑战。特别是,移植前ECMO的使用正在增加,在精心规划的支持下,在LT之前谨慎引入ECMO,有可能优化患者的预后。肝移植患者的ECMO管理具有挑战性。需要更多的研究和经验来改进技术和改善患者的治疗效果。此外,决策必须根据每位患者的独特情况量身定制,并且必须为后续步骤制定清晰、实用和明确的计划。
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The applications of ECMO in liver transplant recipients

Extracorporeal membrane oxygenation (ECMO) has emerged as a vital instrument for sustaining respiratory and cardiac functions when traditional methods have failed. Its function in managing acute pulmonary and cardiac challenges during liver transplantation (LT) has expanded significantly. While ECMO was initially viewed as a rescue strategy for acute intraoperative or posttransplant complications, its application now also encompasses the pretransplant stage of LT. Our review aims to thoroughly summarize both research and specific cases where ECMO has been utilized across pre- and perioperative phases in liver transplant recipients. By assessing the published literature, we discuss specific indications, the types of ECMO employed, their outcomes, and the unique challenges of applying ECMO during LT. In particular, the pretransplant use of ECMO is increasing, and its prudent introduction prior to LT, supported by meticulous planning, has the potential to optimize patient outcomes. It is challenging to manage liver transplant patients on ECMO. More research and experience are needed to refine the techniques and improve patient outcomes. Furthermore, decision-making must be tailored to each patient's unique circumstances, and a clear, practical, and well-defined plan for subsequent steps is essential.

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来源期刊
Transplantation Reviews
Transplantation Reviews IMMUNOLOGY-TRANSPLANTATION
CiteScore
7.50
自引率
2.50%
发文量
40
审稿时长
29 days
期刊介绍: Transplantation Reviews contains state-of-the-art review articles on both clinical and experimental transplantation. The journal features invited articles by authorities in immunology, transplantation medicine and surgery.
期刊最新文献
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